SCHEMBL2327784

SCHEMBL2327784

CC(F)C(F)(F)C(F)(F)[Sn](OCc1ccccc1)(C(F)(F)C(F)(F)C(C)F)C(F)(F)C(F)(F)C(C)F

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
IDO1 P14902 1/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPK1 P28482 2/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
TRPA1 O75762 1/20 0.33
AGXT P21549 1/20 0.32
BCHE P06276 2/20 0.32
CA1 P00915 1/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SLC6A2 P23975 2/20 0.32
TAAR1 Q96RJ0 2/20 0.32
MAOA P21397 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2328694 0.87 TSHR (0.35) TSHRIDO1ALDH1A1MAPK1LMNA
SCHEMBL2326009 0.84 SIGMAR1 (0.36) TSHRIDO1CA1SIGMAR1
SCHEMBL2345113 0.84 TSHR (0.33) TSHRIDO1ALDH1A1MAPK1LMNA
SCHEMBL2325875 0.75 TSHR (0.39) TSHRIDO1ALDH1A1LMNAAGXT
SCHEMBL2331799 0.73 TSHR (0.38) TSHRIDO1ALDH1A1LMNAAGXT
SCHEMBL2331794 0.72 TSHR (0.36) TSHRIDO1ALDH1A1LMNAAGXT
SCHEMBL2322208 0.71
SCHEMBL2331798 0.69 TSHR (0.36) TSHRIDO1ALDH1A1MAPK1LMNA
SCHEMBL2364087 0.69 TSHR (0.36) TSHRIDO1ALDH1A1MAPK1TRPA1
SCHEMBL2329268 0.69 ALDH1A1 (0.34) TSHRIDO1ALDH1A1MAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1987881-B1 METHOD FOR SEPARATION AND COLLECTION OF DIALKYL TIN DIALKOXIDE ASAHI KASEI CHEMICALS CORP (JP) 2011-08-17 EP disclosed
US-7842828-B2 Method for separating out and recovering dialkyltin dialkoxide ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-11-30 US disclosed
US-20100160662-A1 Method for Separating Out and Recovering Dialkyltin Dialkoxide ASAHI KASEI KABUSHIKI KAISHA (JP) 2010-06-24 US disclosed
EP-1987881-A1 METHOD FOR SEPARATION AND COLLECTION OF DIALKYL TIN DIALKOXIDE Asahi Kasei Chemicals Corporation (JP) 2008-11-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160662-A1 Method for Separating Out and Recovering Dialkyltin Dialkoxide ALOX5, ALOX15B, ALOX15 TSHR 3272/4885IDO1 2152/4885ALDH1A1 970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.