SCHEMBL23296385

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19909130	0.89	AURKA (0.34)	LMNANCOA1NCOA3POLBHTT
	SCHEMBL19909374	0.87	PDE10A (0.39)	NTRK1PIM1ACVR1
	SCHEMBL19909132	0.86	PDE9A (0.37)	LMNANCOA1NCOA3POLBHTT
	SCHEMBL19909303	0.85	ALDH1A1 (0.38)	LMNAHTTSMN1; SMN2KDM4EALDH1A1
	SCHEMBL19908916	0.85	TDP1 (0.35)	LMNANCOA1NCOA3POLBHTT
	SCHEMBL19909065	0.84	ALDH1A1 (0.40)	POLBSMN1; SMN2KDM4EALDH1A1HPGD
	SCHEMBL21414110	0.84	ALDH1A1 (0.34)	LMNANCOA1NCOA3POLBHTT
	SCHEMBL19908943	0.84	ALDH1A1 (0.42)	NCOA1NCOA3SMN1; SMN2HIF1AKDM4E
	SCHEMBL23268023	0.84	LMNA (0.38)	LMNANCOA1NCOA3POLBHTT
	SCHEMBL19917582	0.83	ALDH1A1 (0.41)	ALDH1A1BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.