Sugi Predict

Sugi Predict / Compounds / SCHEMBL19909374

SCHEMBL19909374

SCHEMBL19909374

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1cc(-c2ccnc(C)c2)cc(-n2c3ccc(C)cc3c3cc(C)ccc32)c1C#N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDE10A Q9Y233 1/20 0.39
▸ NTRK1 P04629 2/20 0.36
▸ PIM1 P11309 2/20 0.36
▸ ACVR1 Q04771 1/20 0.36
▸ UHRF1 Q96T88 1/20 0.36
▸ DYRK1A Q13627 4/20 0.35
▸ AAK1 Q2M2I8 2/20 0.33
▸ GRM5 P41594 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ MAP4K4 O95819 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ PSEN1 P49768 3/20 0.33
▸ PSEN2 P49810 3/20 0.33
▸ APH1B Q8WW43 3/20 0.33
▸ NCSTN Q92542 3/20 0.33
▸ APH1A Q96BI3 3/20 0.33
▸ PSENEN Q9NZ42 3/20 0.33
▸ CLK1 P49759 3/20 0.32
▸ PIK3R2 O00459 1/20 0.32
▸ LRRK2 Q5S007 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23296385 0.87 LMNA (0.36) NTRK1PIM1ACVR1
SCHEMBL19909075 0.87 PDE10A (0.41) PDE10ANTRK1PIM1DYRK1AMAP4K4
SCHEMBL19909302 0.87 PDE10A (0.37) PDE10ADYRK1AAAK1MAP4K4CYP3A4
SCHEMBL19908916 0.86 TDP1 (0.35) PDE10AGAALRRK2
SCHEMBL19909366 0.84 PDE10A (0.41) PDE10ANTRK1PIM1DYRK1AMAP4K4
SCHEMBL19909471 0.83 PSEN1 (0.38) PDE10ADYRK1AMAP4K4CYP3A4PSEN1
SCHEMBL19909062 0.81 PIK3CD (0.39) PDE10ANTRK1PIM1ACVR1AAK1
SCHEMBL19909047 0.81 CYP11B2 (0.38) PIK3R2
SCHEMBL19909140 0.81 PDE10A (0.37) PDE10AMAP4K4CYP3A4PSEN1PSEN2
SCHEMBL21414110 0.80 ALDH1A1 (0.34) GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 — — US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 — — US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 — — US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 — — US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 — — US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 PDE10A 2467/4885NTRK1 2416/4885PIM1 1720/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 PDE10A 4550/4885NTRK1 3271/4885PIM1 1308/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 PDE10A 2467/4885NTRK1 2416/4885PIM1 1720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.