Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300884 | 0.86 | CA12 (0.42) | MEN1HPGDKMT2AALDH1A1LMNA | |
| SCHEMBL7273843 | 0.84 | SMN1; SMN2 (0.48) | MEN1HPGDKMT2ASRD5A2ALDH1A1 | |
| SCHEMBL23767395 | 0.84 | CES2 (0.47) | CES2HPGDTSHRLMNAGAA | |
| SCHEMBL1696262 | 0.81 | KDM4E (0.42) | CES2CES1MEN1HPGDTSHR | |
| SCHEMBL159204 | 0.81 | KDM4E (0.42) | CES2CES1MEN1HPGDTSHR | |
| SCHEMBL13455758 | 0.81 | SMN1; SMN2 (0.44) | MEN1HPGDKMT2AALDH1A1LMNA | |
| SCHEMBL8824297 | 0.80 | CYP19A1 (0.41) | MEN1KMT2ANPC1LMNAMAPT | |
| SCHEMBL18162174 | 0.80 | ALDH1A1 (0.35) | MEN1HPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL13073460 | 0.80 | MLYCD (0.32) | PRSS1ACR | |
| SCHEMBL13198707 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667621-B2 | Antiestrogen compounds | STEVENS INSTITUTE OF TECHNOLOGY (US) | 2023-06-06 | — | — | US | disclosed |
| US-20210130320-A1 | ANTIESTROGEN COMPOUNDS | STEVENS INSTITUTE OF TECHNOLOGY (US) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667621-B2 | Antiestrogen compounds | ESR1, ESR2, ESRRG | CES2 2344/4885CES1 1306/4885MEN1 2747/4885 |
| US-20210130320-A1 | ANTIESTROGEN COMPOUNDS | ESR1, ESR2, ESRRG | CES2 2344/4885CES1 1306/4885MEN1 2747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.