Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865185 | 0.92 | ALDH1A1 (0.46) | CRHBPCRHR2ALDH1A1KDM4EGAA | |
| SCHEMBL13748419 | 0.88 | TSHR (0.59) | CRHBPCRHR2ALDH1A1KDM4ETSHR | |
| SCHEMBL13748038 | 0.88 | TSHR (0.59) | CRHBPCRHR2ALDH1A1KDM4ETSHR | |
| SCHEMBL13748820 | 0.88 | TSHR (0.59) | CRHBPCRHR2ALDH1A1KDM4ETSHR | |
| SCHEMBL8849586 | 0.88 | TSHR (0.59) | CRHBPCRHR2ALDH1A1KDM4ETSHR | |
| SCHEMBL151680 | 0.88 | TSHR (0.59) | CRHBPCRHR2ALDH1A1KDM4ETSHR | |
| SCHEMBL510240 | 0.84 | ALDH1A1 (0.62) | ALDH1A1KDM4EGAATSHRABCG2 | |
| SCHEMBL9481712 | 0.84 | ALDH1A1 (0.62) | ALDH1A1KDM4EGAATSHRABCG2 | |
| SCHEMBL15807463 | 0.82 | TSHR (0.52) | CRHBPCRHR2ALDH1A1KDM4ETSHR | |
| SCHEMBL16484549 | 0.82 | TSHR (0.52) | CRHBPCRHR2ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230001119-A1 | SYSTEMS AND METHODS FOR INCREASING NITROGEN MONOXIDE CONCENTRATION AND REMOVING NITROGEN DIOXIDE FROM A GAS STREAM | Third Pole, Inc. (US) | 2023-01-05 | — | — | US | disclosed |
| WO-2021087382-A1 | SYSTEMS AND METHODS FOR INCREASING NITROGEN MONOXIDE CONCENTRATION AND REMOVING NITROGEN DIOXIDE FROM A GAS STREAM | Third Pole, Inc. (US) | 2021-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230001119-A1 | SYSTEMS AND METHODS FOR INCREASING NITROGEN MONOXIDE CONCENTRATION AND REMOVING NITROGEN DIOXIDE FROM A GAS STREAM | NOS2, NOS3, NOS1 | CRHBP 1044/4885CRHR2 1523/4885ALDH1A1 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.