SCHEMBL233930

SCHEMBL233930

CCO[Si](CCc1ccccc1CC#N)(OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
ATP4A P20648 1/20 0.32
ATP4B P51164 1/20 0.32
CYP4F2 P78329 1/20 0.30
CYP4A11 Q02928 1/20 0.30
FFAR1 O14842 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL307120 0.86 CYP4F2 (0.37) ALDH1A1HPGDCYP4F2CYP4A11
SCHEMBL233078 0.83 ALDH1A1 (0.38) ALDH1A1HPGDATP4AATP4BFFAR1
SCHEMBL7906863 0.78 TAAR1 (0.33)
SCHEMBL3341059 0.78 CYP4F2 (0.33) ALDH1A1CYP4F2CYP4A11
SCHEMBL11651264 0.76 TAAR1 (0.47) ALDH1A1HPGD
SCHEMBL7781555 0.75 ALDH1A1 (0.44) ALDH1A1HPGDATP4AATP4BFFAR1
SCHEMBL6561657 0.75
SCHEMBL22245281 0.75 TAAR1 (0.47) ALDH1A1
SCHEMBL16669513 0.75 HTR1A (0.46)
SCHEMBL11600164 0.75 ALDH1A1 (0.40) ALDH1A1HPGDATP4AATP4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same FITZHUGH ANTHONY 2007-04-19 US claimed
CN-114055975-A Ink jet recording method and ink jet recording apparatus 精工爱普生株式会社 2022-02-18 CN disclosed
US-10259208-B2 Three-dimensional shaped object manufacturing device, method for manufacturing three-dimensional shaped object, and three-dimensional shaped object SEIKO EPSON CORPORATION (JP) 2019-04-16 US disclosed
US-9579852-B2 Method for manufacturing three-dimensional shaped object SEIKO EPSON CORPORATION (JP) 2017-02-28 US disclosed
US-9537052-B2 Coated phosphors and light emitting devices including the same CREE, INC. (US) 2017-01-03 US disclosed
US-20160339602-A1 METHOD OF MANUFACTURING THREE-DIMENSIONAL STRUCTURE, THREE-DIMENSIONAL STRUCTURE MANUFACTURING APPARATUS, AND THREE-DIMENSIONAL STRUCTURE SEIKO EPSON CORPORATION (JP) 2016-11-24 US disclosed
US-20160263829-A1 THREE-DIMENSIONAL MODELING APPARATUS, MANUFACTURING METHOD, AND COMPUTER PROGRAM SEIKO EPSON CORPORATION (JP) 2016-09-15 US disclosed
US-9415545-B2 Method of manufacturing three-dimensional shaped object SEIKO EPSON CORPORATION (JP) 2016-08-16 US disclosed
US-20160107385-A1 THREE-DIMENSIONAL SHAPED OBJECT MANUFACTURING METHOD AND THREE-DIMENSIONAL SHAPED OBJECT SEIKO EPSON CORPORATION (JP) 2016-04-21 US disclosed
EP-2714840-B1 COATED PHOSPHORS AND LIGHT EMITTING DEVICES INCLUDING THE SAME CREE INC (US) 2016-04-13 EP disclosed
WO-2002059591-A9 SOL-GEL OPEN TUBULAR ODS COLUMNS WITH CHARGED INNER SURFACE FOR CAPILLARY ELECTROCHROMATOGRAPHY UNIV SOUTH FLORIDA (US) 2004-06-03 WO disclosed
WO-2004012874-A1 CROSS-LINKED NITRIC OXIDE-RELEASING POLYAMINE COATED SUBSTRATES, COMPOSITIONS COMPRISING SAME AND METHOD OF MAKING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2004-02-12 WO disclosed
US-20030213732-A1 Sol-Gel monolithic column with optical window and method of making SOUTH FLORIDA, UNIVERSITY OF 2003-11-20 US disclosed
US-20030180551-A1 Conductive emulsion for preparing surface for powder coating NORTHERN ILLINOIS UNIVERSITY 2003-09-25 US disclosed
US-20030075447-A1 Sol-gel open tubular ODS columns with charged inner surface for capillary electrochromatography UNIVERSITY OF SOUTH FLORIDA 2003-04-24 US disclosed
WO-2002094410-A1 SOL-GEL DENDRON SEPARATION AND EXTRACTION CAPILLARY COLUMN UNIVERSITY OF SOUTH FLORIDA (US) 2002-11-28 WO disclosed
US-20020150923-A1 Sample preconcentration tubes with sol-gel surface coatings and/or sol-gel monolithic beds UNIVERSITY OF SOUTH FLORIDA, THE 2002-10-17 US disclosed
WO-2002072225-A1 HIGH EFFICIENCY SOL-GEL GAS CHROMATOGRAPHY COLUMN UNIVERSITY OF SOUTH FLORIDA (US) 2002-09-19 WO disclosed
WO-2002059591-A1 SOL-GEL OPEN TUBULAR ODS COLUMNS WITH CHARGED INNER SURFACE FOR CAPILLARY ELECTROCHROMATOGRAPHY UNIVERSITY OF SOUTH FLORIDA (US) 2002-08-01 WO disclosed
WO-2001058562-A1 SOL-GEL MONOLITHIC COLUMN WITH OPTICAL WINDOW AND METHOD OF MAKING UNIVERSITY OF SOUTH FLORIDA (US) 2001-08-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same NOS2, NOS1, NOS3 ALDH1A1 2127/4885HPGD 304/4885ATP4A 4397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.