Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9936848 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRTHRB | |
| SCHEMBL25263210 | 0.72 | ALDH1A1 (0.50) | ALDH1A1TSHRTHRBPOLB | |
| SCHEMBL810202 | 0.72 | — | — | |
| SCHEMBL3623152 | 0.71 | — | — | |
| Alcohol SCHEMBL6463080 | 0.71 | ALDH1A1 (0.48) | ALDH1A1TSHRTHRB | |
| SCHEMBL22123111 | 0.71 | CES2 (0.47) | CES2ALDH1A1TSHRPOLB | |
| SCHEMBL28992167 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRB | |
| SCHEMBL11129013 | 0.71 | ALDH1A1 (0.36) | ALDH1A1TSHRTHRBPOLB | |
| Ether SCHEMBL23000652 | 0.70 | MAPT (0.38) | CES2ALDH1A1TSHRTHRB | |
| SCHEMBL101044 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4011874-A1 | SUBSTITUTED PYRAZOLO PIPERIDINE CARBOXYLIC ACIDS | Bayer Aktiengesellschaft (DE) | 2022-06-15 | — | — | EP | disclosed |
| US-10993947-B2 | Treatment of skin lesions | TORQUR (CH) | 2021-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10993947-B2 | Treatment of skin lesions | CXCR3, CCR3, C3AR1 | CES2 793/4885ALDH1A1 4115/4885TSHR 364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.