Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | C5 | P01031 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL23320430 | 0.82 | NAMPT (0.54) | NAMPTALDH1A1GAAKMT2ARAB9A | |
| Formamide SCHEMBL23320517 | 0.73 | NAMPT (0.45) | NAMPTALDH1A1TSHRGAAKMT2A | |
| SCHEMBL23320480 | 0.72 | ALDH1A1 (0.53) | NAMPTALDH1A1TSHRGAAKMT2A | |
| SCHEMBL23320400 | 0.67 | NAMPT (0.66) | NAMPTALDH1A1TSHRKMT2AHSD17B10 | |
| SCHEMBL11615932 | 0.66 | HSD17B10 (0.79) | NAMPTALDH1A1TSHRGAAKMT2A | |
| Formamide SCHEMBL23320541 | 0.65 | ALDH1A1 (0.48) | NAMPTALDH1A1TSHRGAAKMT2A | |
| SCHEMBL11615821 | 0.65 | NAMPT (0.64) | NAMPTALDH1A1TSHRKMT2AHSD17B10 | |
| Formamide SCHEMBL23320449 | 0.64 | ALDH1A1 (0.43) | NAMPTALDH1A1TSHRGAAKMT2A | |
| Formamide SCHEMBL23320479 | 0.63 | EYA3 (0.46) | ALDH1A1TSHRKMT2AHSD17B10LMNA | |
| SCHEMBL28195508 | 0.63 | ALDH1A1 (0.51) | ALDH1A1TSHRKMT2AHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |