Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL23320515 | 0.83 | NAMPT (0.52) | NAMPTROCK2ROCK1NPY5R | |
| Formamide SCHEMBL23320428 | 0.78 | L3MBTL1 (0.52) | TSHRKMT2A | |
| Formamide SCHEMBL23320426 | 0.72 | ALDH1A1 (0.47) | ALDH1A1TSHRPPARGNAMPTHSD17B10 | |
| SCHEMBL11615932 | 0.71 | HSD17B10 (0.79) | ALDH1A1TSHRNAMPTHSD17B10ROCK2 | |
| SCHEMBL23320508 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRPPARGNAMPTHSD17B10 | |
| SCHEMBL4531077 | 0.70 | HSD17B10 (0.70) | ALDH1A1TSHRNAMPTHSD17B10ROCK2 | |
| SCHEMBL4519247 | 0.70 | HSD17B10 (0.70) | ALDH1A1TSHRNAMPTHSD17B10ROCK2 | |
| Formamide SCHEMBL23320507 | 0.68 | ALDH1A1 (0.62) | ALDH1A1HSD17B10LMNAKMT2A | |
| SCHEMBL23320400 | 0.67 | NAMPT (0.66) | ALDH1A1TSHRPPARGNAMPTHSD17B10 | |
| SCHEMBL23320574 | 0.66 | ROCK2 (0.50) | ALDH1A1TSHRNAMPTHSD17B10ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |