Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL23320358 | 0.85 | NAMPT (0.52) | NAMPTMAPK1MAPK13MAPK12MAPK11 | |
| Formamide SCHEMBL23320517 | 0.73 | NAMPT (0.45) | ALDH1A1TSHRNAMPTGAAMAPK1 | |
| SCHEMBL23320454 | 0.71 | ALDH1A1 (0.48) | ALDH1A1TSHRNAMPTGAAMAPK1 | |
| SCHEMBL11615932 | 0.70 | HSD17B10 (0.79) | ALDH1A1TSHRNAMPTGAAMAPK1 | |
| SCHEMBL23320366 | 0.69 | NAMPT (0.66) | ALDH1A1TSHRNAMPTGAAMAPK1 | |
| Formamide SCHEMBL23320434 | 0.69 | ELANE (0.39) | ALDH1A1GAAMAPK1HSD17B10KMT2A | |
| Formamide SCHEMBL23320426 | 0.67 | ALDH1A1 (0.47) | ALDH1A1TSHRNAMPTGAAMAPK1 | |
| SCHEMBL16965538 | 0.64 | MAPK1 (0.61) | MAPK1 | |
| Formamide SCHEMBL23320348 | 0.64 | NAMPT (0.48) | ALDH1A1TSHRNAMPTGAAMAPK1 | |
| SCHEMBL4519247 | 0.64 | HSD17B10 (0.70) | ALDH1A1TSHRNAMPTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |