Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320396 | 0.92 | NAMPT (0.36) | NAMPTADRA2BADORA1ADORA2AQPCT | |
| SCHEMBL23320568 | 0.82 | SCN9A (0.33) | NAMPTADORA1SCN9AADORA3MAPT | |
| SCHEMBL23320379 | 0.79 | NAMPT (0.41) | NAMPTADORA1ADORA2AADORA3MAPT | |
| SCHEMBL30943200 | 0.75 | NAMPT (0.67) | NAMPT | |
| SCHEMBL24042559 | 0.75 | NAMPT (0.67) | NAMPT | |
| SCHEMBL23320407 | 0.73 | FBP1 (0.38) | ADORA1ADORA2AADORA3MAPTKDM4E | |
| SCHEMBL23320370 | 0.73 | KDM4E (0.43) | ADORA1ADORA2ASCN9AADORA3MAPT | |
| SCHEMBL23320352 | 0.70 | NAMPT (0.42) | NAMPTADORA1ADORA2AQPCTADORA3 | |
| SCHEMBL23320493 | 0.69 | ALDH1A1 (0.38) | TDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL23320485 | 0.69 | CHEK1 (0.37) | HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |