Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 8/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320566 | 0.92 | NAMPT (0.35) | NAMPTQPCTSCN9AADORA1ADORA3 | |
| SCHEMBL23320568 | 0.83 | SCN9A (0.33) | NAMPTSCN9AADORA1ADORA3POLB | |
| SCHEMBL23320352 | 0.79 | NAMPT (0.42) | NAMPTQPCTMAPK14ADORA1ADORA3 | |
| SCHEMBL30943200 | 0.76 | NAMPT (0.67) | NAMPT | |
| SCHEMBL24042559 | 0.76 | NAMPT (0.67) | NAMPT | |
| SCHEMBL23320370 | 0.74 | KDM4E (0.43) | SCN9AADORA1ADORA3MAPTADORA2A | |
| SCHEMBL23320407 | 0.72 | FBP1 (0.38) | ADORA1ADORA3MAPTADORA2A | |
| SCHEMBL23320379 | 0.70 | NAMPT (0.41) | NAMPTMAPK14ADORA1ADORA3MAPT | |
| SCHEMBL23320561 | 0.68 | ALDH1A1 (0.39) | QPCTPOLBMAPT | |
| SCHEMBL31691593 | 0.67 | POLB (0.37) | SCN9AADORA1ADORA3POLBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | claimed |
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |