Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24775485 | 0.81 | CHRNB2 (0.51) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL24775061 | 0.77 | CHRNA7 (0.35) | CHRNA7DRD2HTR1ACHRNB2CHRNB4 | |
| SCHEMBL28533797 | 0.70 | MEN1 (0.40) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL28526259 | 0.70 | MEN1 (0.40) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL27397494 | 0.70 | HTR1D (0.44) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL24737112 | 0.69 | CHRNA7 (0.33) | CHRNA7 | |
| SCHEMBL24774767 | 0.69 | LIPG (0.38) | CHRNA7DRD2HTR1A | |
| SCHEMBL4825129 | 0.68 | HTR1D (0.43) | DRD2DRD1DRD4DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL7994679 | 0.68 | HTR1D (0.43) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL12932568 | 0.68 | CHRNB2 (0.54) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021083135-A1 | Bcl-2 INHIBITORS | BEIGENE, LTD. (KY) | 2021-05-06 | — | — | WO | disclosed |