Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT1 | P34896 | 2/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 10/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 3/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19838175 | 0.86 | SHMT1 (0.35) | SHMT1SHMT2P2RX7ERAP1FABP4 | |
| SCHEMBL19838161 | 0.84 | SHMT1 (0.41) | SHMT1SHMT2P2RX7ERAP1FABP4 | |
| SCHEMBL30554129 | 0.82 | SHMT1 (0.35) | SHMT1SHMT2P2RX7ERAP1FABP4 | |
| SCHEMBL2362122 | 0.82 | HCRTR2 (0.32) | — | |
| SCHEMBL19838268 | 0.82 | SHMT1 (0.35) | SHMT1SHMT2P2RX7AKR1B1ERAP1 | |
| SCHEMBL2355303 | 0.80 | HCRTR2 (0.35) | SHMT1SHMT2AKR1B1 | |
| SCHEMBL19838169 | 0.78 | PYGL (0.33) | SHMT1SHMT2 | |
| SCHEMBL2362279 | 0.78 | HCRTR2 (0.33) | AKR1B1 | |
| SCHEMBL21049517 | 0.76 | SHMT1 (0.42) | SHMT1SHMT2P2RX7ERAP1FABP4 | |
| SCHEMBL19838170 | 0.76 | PYGL (0.36) | SHMT1SHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220267291-A1 | PROCESS FOR PREPARING ESTERS OF N-ACYLATED AMINO ACIDS WITH ACID-LABILE KETO PROTECTIVE GROUP FUNCTIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-08-25 | — | — | US | disclosed |
| US-11384061-B2 | Process for preparing esters of N-acylated amino acids with acid-labile keto protective group functions | BAYER AKTIENGESELLSCHAFT (DE) | 2022-07-12 | — | — | US | disclosed |
| US-20210139450-A1 | PROCESS FOR PREPARING ESTERS OF N-ACYLATED AMINO ACIDS WITH ACID-LABILE KETO PROTECTIVE GROUP FUNCTIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11384061-B2 | Process for preparing esters of N-acylated amino acids with acid-labile keto protective group functions | AADAT, DNPEP, BCKDK | SHMT1 1260/4885SHMT2 1087/4885P2RX7 4878/4885 |
| US-20210139450-A1 | PROCESS FOR PREPARING ESTERS OF N-ACYLATED AMINO ACIDS WITH ACID-LABILE KETO PROTECTIVE GROUP FUNCTIONS | AADAT, DNPEP, BCKDK | SHMT1 1260/4885SHMT2 1087/4885P2RX7 4878/4885 |
| US-20220267291-A1 | PROCESS FOR PREPARING ESTERS OF N-ACYLATED AMINO ACIDS WITH ACID-LABILE KETO PROTECTIVE GROUP FUNCTIONS | AADAT, DNPEP, BCKDK | SHMT1 1260/4885SHMT2 1087/4885P2RX7 4878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.