Sugi Predict

Sugi Predict / Compounds / Hydrochloric Acid

Hydrochloric Acid

Hydrochloric Acid

SCHEMBL23326872

Cc1cccc(O)c1[N+]1=CN(c2c(C(C)C)cccc2C(C)C)CC1.[Cl-]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 known ✓ P23975 1/20 0.33
▸ ANPEP P15144 2/20 0.36
▸ DPP4 P27487 2/20 0.36
▸ GABRA1 P14867 2/20 0.36
▸ GABRB2 P47870 2/20 0.36
▸ TSHR P16473 2/20 0.33
▸ CYP1A2 P05177 2/20 0.33
▸ CYP3A4 P08684 2/20 0.33
▸ HPGD P15428 2/20 0.33
▸ FAAH O00519 1/20 0.33
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ GABRB1 P18505 1/20 0.33
▸ GABRG2 P18507 1/20 0.33
▸ PTGS1 P23219 1/20 0.33
▸ HTR2C P28335 1/20 0.33
▸ GABRB3 P28472 1/20 0.33
▸ GABRA5 P31644 1/20 0.33
▸ GABRA3 P34903 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL23326869 0.87 GABRA1 (0.36) ANPEPDPP4GABRA1GABRB2TSHR
Hydrochloric Acid SCHEMBL739370 0.85 DPP4 (0.33) ANPEPDPP4GABRA1GABRB2TSHR
Hydrochloric Acid SCHEMBL1727633 0.84 DPP4 (0.32) ANPEPDPP4GABRA1GABRB2TSHR
SCHEMBL819459 0.83 DPP4 (0.33) ANPEPDPP4GABRA1GABRB2TSHR
Hydrochloric Acid SCHEMBL3156607 0.83 GABRA1 (0.40) ANPEPDPP4GABRA1GABRB2TSHR
SCHEMBL12503773 0.82 DPP4 (0.33) ANPEPDPP4GABRA1GABRB2TSHR
SCHEMBL2149891 0.82 DPP4 (0.33) ANPEPDPP4GABRA1GABRB2TSHR
Hydrochloric Acid SCHEMBL820071 0.82 ANPEP (0.32) ANPEPDPP4TSHRALDH1A1ALOX15
Hydrochloric Acid SCHEMBL1609146 0.80 ALDH1A1 (0.36) ANPEPDPP4TSHRALDH1A1ALOX15
SCHEMBL1047506 0.80 ANPEP (0.33) ANPEPDPP4TSHRALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12440831-B2 Longer-lived ruthenium olefin metathesis catalysts supported by hemi-labile carbene ligands The Trustees of the California State University (US) 2025-10-14 — — US disclosed
US-20210138444-A1 Longer-Lived Ruthenium Olefin Metathesis Catalysts Supported by Hemi-Labile Carbene Ligands The California State University - Northridge (US) 2021-05-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12440831-B2 Longer-lived ruthenium olefin metathesis catalysts supported by hemi-labile carbene ligands SQLE, MAX, MGLL SLC6A2 4276/4885ANPEP 4638/4885DPP4 4324/4885
US-20210138444-A1 Longer-Lived Ruthenium Olefin Metathesis Catalysts Supported by Hemi-Labile Carbene Ligands SQLE, MAX, MGLL SLC6A2 4276/4885ANPEP 4638/4885DPP4 4324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.