⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4732262 | 0.96 | — | — | |
| SCHEMBL29019092 | 0.86 | — | — | |
| SCHEMBL945654 | 0.75 | — | — | |
| SCHEMBL12808218 | 0.75 | — | — | |
| SCHEMBL1828973 | 0.75 | — | — | |
| SCHEMBL6255566 | 0.72 | ALDH1A1 (0.30) | — | |
| SCHEMBL1556023 | 0.72 | ALDH1A1 (0.30) | — | |
| Trifluoroacetamide SCHEMBL28054279 | 0.72 | ALDH1A1 (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL7764428 | 0.70 | ACHE (0.38) | — | |
| SCHEMBL322433 | 0.70 | THRB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 729 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957042-B | Synthesis process of 2, 2-trifluoroacetamidine | 苏州莱克施德药业有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-118084731-A | Synthesis method of trifluoroacetamidine | 上海予君生物科技发展有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-112661667-B | Preparation method of trifluoroacetamidine | 浦拉司科技（上海）有限责任公司 | 2023-02-03 | — | — | CN | claimed |
| CN-114957042-A | Synthesis process of 2,2, 2-trifluoroacetamidine | 苏州莱克施德药业有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-112661667-A | Preparation method of trifluoroacetamidine | 浦拉司科技（上海）有限责任公司 | 2021-04-16 | — | — | CN | claimed |
| CN-112490369-A | Preparation method of semiconductor material, perovskite semiconductor device and preparation method thereof | 北京大学深圳研究生院 | 2021-03-12 | — | — | CN | claimed |
| CN-109970648-A | Amidine and the like is catalyzed the list guard method of diaza cycloaliphatic ring tertbutyloxycarbonyl | 西华大学 | 2019-07-05 | — | — | CN | claimed |
| EP-1567508-B1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CHEILJEDANG CORP (KR) | 2011-02-02 | — | — | EP | claimed |
| EP-1567508-A4 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CHEILJEDANG CORP (KR) | 2008-12-10 | — | — | EP | claimed |
| EP-1539718-A4 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CORP (KR) | 2007-08-01 | — | — | EP | claimed |
| EP-1567508-A1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ Corporation (KR) | 2005-08-31 | — | — | EP | claimed |
| EP-1539718-A1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ Corporation (KR) | 2005-06-15 | — | — | EP | claimed |
| WO-2004046121-A1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CORPORATION (KR) | 2004-06-03 | — | — | WO | claimed |
| WO-2004014878-A1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CORPORATION (KR) | 2004-02-19 | — | — | WO | claimed |
| EP-4161642-B1 | N-PHENYLAMINOCARBONYL PYRIDINO- , PYRIMIDINO AND BENZO-TROPANES AS MODULATORS OF GPR65 | PATHIOS THERAPEUTICS LTD (GB) | 2026-05-27 | — | — | EP | disclosed |
| US-12617789-B2 | Small molecular inhibitors of NF-κb inducing kinase | JANSSEN PHARMACEUTICA NV (BE) | 2026-05-05 | — | — | US | disclosed |
| US-12516065-B2 | Tertiary alcohols as PI3K-γ inhibitors | INCYTE CORPORATION (US) | 2026-01-06 | — | — | US | disclosed |
| US-4119781-A | Process for preparing 4-substituted imidazole compounds | SK&F LAB CO. (US) | 1978-10-10 | — | — | US | disclosed |
| US-4097599-A | PESTICIDES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1978-06-27 | — | — | US | disclosed |
| US-4038405-A | MITICIDES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1977-07-26 | — | — | US | disclosed |