Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84416 | 0.82 | RAB9A (0.64) | RAB9ASMN1; SMN2MAPTLMNATP53 | |
| SCHEMBL13650900 | 0.80 | LMNA (0.55) | RAB9ASMN1; SMN2MAPTLMNATP53 | |
| SCHEMBL10806421 | 0.80 | MAPT (0.52) | RAB9ASMN1; SMN2MAPTLMNATP53 | |
| SCHEMBL2564592 | 0.80 | THRB (0.56) | RAB9ASMN1; SMN2MAPTLMNATP53 | |
| SCHEMBL9569337 | 0.80 | MAPT (0.52) | RAB9ASMN1; SMN2MAPTLMNATP53 | |
| SCHEMBL74089 | 0.80 | MAPT (0.52) | RAB9ASMN1; SMN2MAPTLMNATP53 | |
| SCHEMBL9569335 | 0.80 | THRB (0.53) | RAB9ASMN1; SMN2MAPTLMNATP53 | |
| Hydrochloric Acid SCHEMBL11010648 | 0.80 | MAPT (0.49) | RAB9ASMN1; SMN2MAPTLMNATP53 | |
| SCHEMBL11011725 | 0.79 | MAPT (0.51) | RAB9ASMN1; SMN2MAPTLMNATP53 | |
| SCHEMBL5909037 | 0.78 | LMNA (0.53) | RAB9ASMN1; SMN2MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087056-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-05-06 | — | — | WO | disclosed |