Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84416 | 0.88 | RAB9A (0.64) | MAPTTP53RAB9ALMNATSHR | |
| SCHEMBL7763808 | 0.86 | MAPT (0.53) | MAPTTP53RAB9ALMNATSHR | |
| SCHEMBL13650900 | 0.85 | LMNA (0.55) | MAPTTP53RAB9ALMNATSHR | |
| SCHEMBL2564592 | 0.85 | THRB (0.56) | MAPTTP53RAB9ALMNATSHR | |
| SCHEMBL74089 | 0.85 | MAPT (0.52) | MAPTTP53RAB9ALMNATSHR | |
| SCHEMBL10806421 | 0.85 | MAPT (0.52) | MAPTTP53RAB9ALMNATSHR | |
| SCHEMBL9569335 | 0.85 | THRB (0.53) | MAPTTP53RAB9ALMNATSHR | |
| SCHEMBL5909037 | 0.84 | LMNA (0.53) | MAPTTP53RAB9ALMNATSHR | |
| SCHEMBL20893101 | 0.83 | TP53 (0.67) | MAPTTP53RAB9ALMNATSHR | |
| SCHEMBL9569322 | 0.82 | TP53 (0.73) | MAPTTP53RAB9ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524055-A1 | Imidazo(2,1-b)benzothiazole-3-acetamide derivatives, process for their preparation and their therapeutical use | SYNTHELABO (FR) | 1993-01-20 | — | — | EP | disclosed |