Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.53 |
| ▸ | GHSR | Q92847 | 12/20 | 0.46 |
| ▸ | REN | P00797 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23335238 | 0.88 | SLC15A2 (0.49) | SLC15A2GHSRREN | |
| SCHEMBL29531079 | 0.79 | SLC15A2 (0.63) | SLC15A2GHSRREN | |
| SCHEMBL29429145 | 0.79 | SLC15A2 (0.63) | SLC15A2GHSRREN | |
| SCHEMBL23335233 | 0.79 | SIRT6 (0.47) | — | |
| SCHEMBL30447227 | 0.79 | SIRT6 (0.47) | — | |
| SCHEMBL18862078 | 0.76 | SLC15A2 (0.56) | SLC15A2GHSRREN | |
| SCHEMBL23335144 | 0.75 | FURIN (0.47) | — | |
| SCHEMBL15080458 | 0.73 | REN (0.63) | SLC15A2REN | |
| SCHEMBL22217022 | 0.73 | SLC15A2 (0.79) | SLC15A2GHSRREN | |
| SCHEMBL29444049 | 0.72 | SLC15A2 (0.65) | SLC15A2GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128743-A1 | TRANSGLUTAMINASE CONJUGATION METHOD AND LINKER | PAUL SCHERRER INSTITUT (CH) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128743-A1 | TRANSGLUTAMINASE CONJUGATION METHOD AND LINKER | TGM3, TGM2, TGM1 | SLC15A2 1512/4885GHSR 1350/4885REN 3826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.