Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CD38 | P28907 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2330315 | 0.89 | HPGD (0.44) | HPGDKMT2ATP53GLACD38 | |
| SCHEMBL2333574 | 0.81 | MAPT (0.43) | TP53ROCK2ROCK1 | |
| SCHEMBL2333876 | 0.80 | TRPV1 (0.45) | HPGDKMT2A | |
| SCHEMBL2328736 | 0.80 | TRPV1 (0.45) | HPGDKMT2ARXFP1MEN1 | |
| SCHEMBL2324504 | 0.78 | MT-CO2 (0.39) | HPGDKMT2ATP53CD38PLA2G1B | |
| SCHEMBL2332116 | 0.73 | MEN1 (0.43) | HPGDKMT2ATP53KDM4EALDH1A1 | |
| SCHEMBL2329485 | 0.73 | MEN1 (0.43) | HPGDKMT2ATP53KDM4EALDH1A1 | |
| SCHEMBL1754354 | 0.71 | MAPT (0.43) | TP53ROCK2ROCK1 | |
| SCHEMBL2330077 | 0.68 | SMN1; SMN2 (0.47) | HPGDKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL1754182 | 0.67 | EPHX2 (0.47) | KMT2ATP53ALDH1A1MEN1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222631-B1 | SUBSTITUTED PHENYLMETHYL BICYCLOCARBOXYAMIDE COMPOUNDS | PFIZER (US) | 2011-08-17 | — | — | EP | claimed |