SCHEMBL2333725

SCHEMBL2333725

CN(C)CCC(C(=O)O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.39
HRH1 P35367 2/20 0.39
MAPT P10636 1/20 0.36
CHRM1 P11229 2/20 0.36
CHRM3 P20309 2/20 0.36
AKR1A1 P14550 1/20 0.36
HTR2C P28335 1/20 0.36
ADRA1A P35348 1/20 0.36
DRD3 P35462 1/20 0.36
SLC6A3 Q01959 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ENPEP Q07075 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNA4 P43681 1/20 0.36
NOS3 P29474 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15711001 0.97 HTR2A (0.38) HTR2AHRH1MAPTCHRM1CHRM3
SCHEMBL15710764 0.84 HTR2A (0.43) HTR2AHRH1NOS3NOS1NOS2
SCHEMBL15711311 0.82 HTR2A (0.42) HTR2AHRH1NOS3NOS1NOS2
SCHEMBL17359140 0.82 ALDH1A1 (0.46) HTR2AHRH1ALDH1A1TSHRKDM4A
SCHEMBL28027517 0.80 ALDH1A1 (0.43) HTR2AHRH1ALDH1A1TSHRKDM4A
SCHEMBL3129317 0.79 TET2 (0.48) HTR2AHRH1MAPTCHRM1CHRM3
SCHEMBL1672355 0.79 GABRR1 (0.52) HTR2AHRH1HDAC1HDAC2ENPEP
SCHEMBL847328 0.79 GABRR1 (0.52) HTR2AHRH1HDAC1HDAC2ENPEP
SCHEMBL15711004 0.77 CYP3A4 (0.39) HTR2AHRH1MAPTCHRM1CHRM3
SCHEMBL1527366 0.77 NOS2 (0.53) NOS3NOS1NOS2ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2740738-B1 PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASE, PREPARATION METHODS AND USES THEREOF BEIJING FSWELCOME TECH DEVELOPMENT CO LTD (CN) 2018-03-28 EP claimed
EP-2740738-A1 PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASE, PREPARATION METHODS AND USES THEREOF Beijing FSwelcome Technology Development Co., Ltd. (CN) 2014-06-11 EP claimed
US-20140142079-A1 PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASES, PREPARATION METHOD AND USE THEREOF BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2014-05-22 US claimed
EP-0050762-B1 PROCESS FOR THE PREPARATION OF VINYLCYCLOPROPANE DERIVATIVES NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1984-06-13 EP claimed
US-12606823-B2 Modified CPF1 guide RNA Breeze Bio, Inc. 2026-04-21 US disclosed
US-12042541-B2 Lipids and compositions for the delivery of therapeutics ARBUTUS BIOPHARMA CORPORATION (CA) 2024-07-23 US disclosed
EP-3757090-B1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORP (CA) 2024-06-12 EP disclosed
US-20240042039-A1 LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORPORATION (CA) 2024-02-08 US disclosed
EP-4241767-A2 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS Arbutus Biopharma Corporation (CA) 2023-09-13 EP disclosed
US-11712476-B2 Lipids and compositions for the delivery of therapeutics ARBUTUS BIOPHARMA CORPORATION (CA) 2023-08-01 US disclosed
EP-3757090-A9 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS Arbutus Biopharma Corporation (CA) 2023-07-19 EP disclosed
US-20220023427-A1 LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORPORATION (CA) 2022-01-27 US disclosed
US-5861428-A ALLEVIATION OF OSTEOARTHRITIS, RHEUMATOID ARTHRITIS, SEPTIC ARTHRITIS, PERIODONTAL DISEASE, CORNEAL ULCERATION, PROTEINURIA, ANEURYSMAL AORTIC DISEASE, DYSTROPHOBIC EPIDERMOLYSIS BULLOSA, INFLAMMATION, OSTEOPENIAS, TEMPERO BAYER CORPORATION (US) 1999-01-19 US disclosed
US-5861427-A ALLEVIATION OF OSTEOARTHRITIS, RHEUMATOID ARTHRITIS, SEPTIC ARTHRITIS, PERIODONTAL DISEASE, CORNEAL ULCERATION, PROTEINURIA, ANEURYSMAL AORTIC DISEASE, DYSTROPHOBIC EPIDERMOLYSIS BULLOSA, CONDITIONS LEADING TO INFLAMMATORY BAYER HEALTHCARE LLC 1999-01-19 US disclosed
US-5859047-A ANTIARTHRITIC AGENTS, NERVOUS SYSTEM DISORDERS BAYER CORPORATION (US) 1999-01-12 US disclosed
US-5854277-A Thiophenebutanoic acid derivatives as matrix metalloprotease inhibitors BAYER CORPORATION (US) 1998-12-29 US disclosed
US-5789434-A ACID, ESTER OR AMIDE DERIVATIVES AS ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS AND REDUCTION OF CARTILAGE DETERIORATION BAYER CORPORATION (US) 1998-08-04 US disclosed
EP-0790974-A1 SUBSTITUTED 4-BIARYLBUTYRIC OR 5-BIARYLPENTANOIC ACIDS AND DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITIORS Bayer Corporation (US) 1997-08-27 EP disclosed
WO-1996015096-A1 SUBSTITUTED 4-BIARYLBUTYRIC OR 5-BIARYLPENTANOIC ACIDS AND DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITIORS BAYER CORPORATION (US) 1996-05-23 WO disclosed
EP-0050762-A1 Process for the preparation of vinylcyclopropane derivatives NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1982-05-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140142079-A1 PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASES, PREPARATION METHOD AND USE THEREOF PCNA, POLI, MKI67 HTR2A 4425/4885HRH1 1880/4885MAPT 2475/4885
US-12606823-B2 Modified CPF1 guide RNA CPSF1, CPSF6, UPF1 HTR2A 3506/4885HRH1 4359/4885MAPT 3342/4885
US-12042541-B2 Lipids and compositions for the delivery of therapeutics PHOSPHO1, MBOAT1, SGMS1 HTR2A 2317/4885HRH1 1737/4885MAPT 2962/4885
US-20220023427-A1 LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS SGMS2, APOB, PHOSPHO1 HTR2A 1476/4885HRH1 2742/4885MAPT 4186/4885
US-11712476-B2 Lipids and compositions for the delivery of therapeutics SGMS2, APOB, PHOSPHO1 HTR2A 1476/4885HRH1 2742/4885MAPT 4186/4885
US-20240042039-A1 LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS PHOSPHO1, MBOAT1, SGMS1 HTR2A 2317/4885HRH1 1737/4885MAPT 2962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.