Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23337964 | 0.78 | ALDH1A1 (0.45) | FGFR4ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL23337972 | 0.77 | TRPV1 (0.42) | ALDH1A1GAASMN1; SMN2MAPTMEN1 | |
| SCHEMBL23337969 | 0.76 | ALDH1A1 (0.46) | FGFR4ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL8635254 | 0.74 | ALDH1A1 (0.51) | FGFR4ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL23337967 | 0.74 | IRAK4 (0.41) | — | |
| SCHEMBL9362813 | 0.73 | MAPT (0.50) | FGFR4ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL8989531 | 0.73 | ALDH1A1 (0.58) | ALDH1A1GAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL11819244 | 0.73 | JUN (0.41) | ALDH1A1GAAMAPTKDM4EL3MBTL1 | |
| SCHEMBL17154863 | 0.72 | MAPT (0.61) | FGFR4ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL23337963 | 0.72 | IRAK4 (0.35) | TDP1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210337797-A1 | PREPARATION OF PYRIDAZINYL AMINE COMPOUND AND APPLICATION THEREOF | Synwill Co., Ltd. (CN) | 2021-11-04 | — | — | US | disclosed |
| EP-3854791-A1 | PREPARATION OF PYRIDAZINYL AMINE COMPOUND AND APPLICATION THEREOF | Synwill Co., Ltd. (CN) | 2021-07-28 | — | — | EP | disclosed |
| WO-2021081923-A1 | 2-PYRIDYLAMINE DERIVATIVE USED AS FUNGICIDE | 江苏中旗科技股份有限公司 | 2021-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210337797-A1 | PREPARATION OF PYRIDAZINYL AMINE COMPOUND AND APPLICATION THEREOF | ACHE, EML4, TOP2A | FGFR4 3887/4885ALDH1A1 2266/4885GAA 2616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.