Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23339687 | 0.79 | CYP1A2 (0.47) | SIGMAR1TMEM97ABCB1CYP1A2CYP2D6 | |
| SCHEMBL7936484 | 0.78 | SIGMAR1 (0.55) | SIGMAR1TMEM97ABCB1 | |
| SCHEMBL6986827 | 0.76 | SIGMAR1 (0.47) | SIGMAR1TMEM97ABCB1 | |
| SCHEMBL5841796 | 0.75 | SIGMAR1 (0.51) | SIGMAR1TMEM97ABCB1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL5842696 | 0.75 | CHRM2 (0.49) | SIGMAR1TMEM97ABCB1 | |
| Hydrochloric Acid SCHEMBL5840933 | 0.74 | SIGMAR1 (0.50) | SIGMAR1TMEM97ABCB1CYP1A2CYP2D6 | |
| SCHEMBL6656817 | 0.73 | SIGMAR1 (0.57) | SIGMAR1TMEM97ABCB1DRD2SLC6A4 | |
| SCHEMBL23339250 | 0.73 | DRD2 (0.55) | SIGMAR1TMEM97DRD2SLC6A4 | |
| SCHEMBL6660619 | 0.72 | SIGMAR1 (0.56) | SIGMAR1TMEM97ABCB1 | |
| SCHEMBL6987164 | 0.72 | SIGMAR1 (0.46) | SIGMAR1TMEM97ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102204-B1 | HIGHLY SELECTIVE SIGMA 1 RECEPTOR LIGANDS AND RADIOLIGANDS AS PROBES IN NOCICEPTIVE PROCESSING AND THE PATHOPHYSIOLOGICAL STUDY OF MEMORY DEFICITS AND COGNITIVE DISORDERS | THE UNIV OF MISSISSIPPI (US) | 2021-05-05 | — | — | EP | disclosed |