SCHEMBL2334032

SCHEMBL2334032

CC(C)(C)OC(=O)N1CCC(c2ccccc2COS(C)(=O)=O)CC1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
STS P08842 2/20 0.48
MAPT P10636 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
GPR119 Q8TDV5 10/20 0.48
THRB P10828 2/20 0.46
GAA P10253 1/20 0.46
KDM4E B2RXH2 2/20 0.46
PKM P14618 1/20 0.46
NAMPT P43490 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22524566 0.89 STS (0.49) STSMAPTSMN1; SMN2GPR119THRB
SCHEMBL29021455 0.87 STS (0.47) STSMAPTSMN1; SMN2GPR119THRB
SCHEMBL3319319 0.86 GPR119 (0.47) STSMAPTSMN1; SMN2GPR119
SCHEMBL29021454 0.86 STS (0.53) STSMAPTSMN1; SMN2GPR119THRB
SCHEMBL2364532 0.85 MEN1 (0.43)
SCHEMBL1513166 0.83 GPR119 (0.53) STSMAPTSMN1; SMN2GPR119THRB
SCHEMBL30233524 0.83 GPR119 (0.53) STSMAPTSMN1; SMN2GPR119THRB
SCHEMBL28059306 0.83 HCRTR2 (0.36) MAPTSMN1; SMN2GPR119
SCHEMBL2553555 0.81 GPR119 (0.54) STSMAPTSMN1; SMN2GPR119THRB
SCHEMBL4675703 0.81 GPR119 (0.51) STSMAPTSMN1; SMN2GPR119THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12239638-B2 Crystalline form of a 4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compound THERAVANCE BIOPHARMA R&D IP, LLC (US) 2025-03-04 US disclosed
EP-4491223-A2 COMPOUND FOR USE IN THE TREATMENT OF NEUROGENIC ORTHOSTATIC HYPOTENSION Theravance Biopharma R&D IP, LLC (US) 2025-01-15 EP disclosed
US-20240316024-A1 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUNDS THERAVANCE BIOPHARMA R&D IP LLC (US) 2024-09-26 US disclosed
EP-3784655-B1 PROCESS FOR PREPARING 2-(1-(TERT-BUTOXYCARBONYL)PIPERIDINE-4-YL)BENZOIC ACID THERAVANCE BIOPHARMA R&D IP LLC (US) 2023-10-04 EP disclosed
US-11723900-B2 4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compounds THERAVANCE BIOPHARMA R&D IP, LLC (US) 2023-08-15 US disclosed
US-11723900-B2 4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compounds THERAVANCE BIOPHARMA R&D IP, LLC (US) 2023-08-15 US disclosed
US-11723900-B2 4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compounds THERAVANCE BIOPHARMA R&D IP, LLC (US) 2023-08-15 US disclosed
US-20230201181-A1 CRYSTALLINE FORM OF A 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUND THERAVANCE BIOPHARMA R&D IP LLC (US) 2023-06-29 US disclosed
US-20230201181-A1 CRYSTALLINE FORM OF A 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUND THERAVANCE BIOPHARMA R&D IP LLC (US) 2023-06-29 US disclosed
US-20230201181-A1 CRYSTALLINE FORM OF A 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUND THERAVANCE BIOPHARMA R&D IP LLC (US) 2023-06-29 US disclosed
US-20100125141-A1 PROCESS FOR PREPARING 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUNDS THERAVANCE BIOPHARMA R&D IP, LLC 2010-05-20 US disclosed
US-20100125141-A1 PROCESS FOR PREPARING 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUNDS THERAVANCE BIOPHARMA R&D IP, LLC 2010-05-20 US disclosed
US-20100125141-A1 PROCESS FOR PREPARING 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUNDS THERAVANCE BIOPHARMA R&D IP, LLC 2010-05-20 US disclosed
US-20100125093-A1 CRYSTALLINE FORM OF A 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUND THERAVANCE BIOPHARMA R&D IP, LLC 2010-05-20 US disclosed
US-20100125093-A1 CRYSTALLINE FORM OF A 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUND THERAVANCE BIOPHARMA R&D IP, LLC 2010-05-20 US disclosed
US-20100125093-A1 CRYSTALLINE FORM OF A 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUND THERAVANCE BIOPHARMA R&D IP, LLC 2010-05-20 US disclosed
US-20100125092-A1 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUNDS THERAVANCE BIOPHARMA R&D IP, LLC 2010-05-20 US disclosed
US-20100125092-A1 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUNDS THERAVANCE BIOPHARMA R&D IP, LLC 2010-05-20 US disclosed
US-20100125092-A1 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUNDS THERAVANCE BIOPHARMA R&D IP, LLC 2010-05-20 US disclosed
WO-2010056939-A1 CRYSTALLINE FORM OF A 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUND THERAVANCE, INC. (US) 2010-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12239638-B2 Crystalline form of a 4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compound REN, PKD2, UACA STS 3401/4885MAPT 131/4885SMN1; SMN2 3197/4885
US-11723900-B2 4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compounds SLC6A2, SLC6A4, HTR6 STS 2041/4885MAPT 1250/4885SMN1; SMN2 1338/4885
US-20100125092-A1 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUNDS SLC6A2, SLC6A4, HTR6 STS 2041/4885MAPT 1250/4885SMN1; SMN2 1338/4885
US-20240316024-A1 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUNDS SLC6A2, SLC6A4, HTR6 STS 2041/4885MAPT 1250/4885SMN1; SMN2 1338/4885
US-20100125141-A1 PROCESS FOR PREPARING 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUNDS SLC6A2, SLC6A4, HTR6 STS 1113/4885MAPT 1337/4885SMN1; SMN2 1362/4885
US-20230201181-A1 CRYSTALLINE FORM OF A 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUND REN, PKD2, UACA STS 3401/4885MAPT 131/4885SMN1; SMN2 3197/4885
US-20100125093-A1 CRYSTALLINE FORM OF A 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUND REN, PKD2, UACA STS 3401/4885MAPT 131/4885SMN1; SMN2 3197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.