SCHEMBL233408

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL236169	0.88	KIF11 (0.35)	CYP2D6HRH4HRH3KIF11LPL
	SCHEMBL232960	0.87	LPL (0.37)	CYP2D6HRH4HRH3KIF11LPL
	SCHEMBL236313	0.85	CYP2D6 (0.39)	CYP2D6HRH4HRH3PTGESTAAR1
	SCHEMBL236621	0.85	MAOA (0.38)	KIF11LPLLIPGPTGESPPARG
	SCHEMBL232755	0.85	PTGES (0.37)	MAPTCYP2D6HRH4HRH3PTGES
	SCHEMBL235253	0.83	TAAR1 (0.35)	CYP2D6HRH4HRH3KIF11LPL
	SCHEMBL235256	0.83	CYP2D6 (0.37)	MAPTCYP2D6HRH4HRH3PTGES
	SCHEMBL233641	0.83	KMT2A (0.38)	MAPTCYP2D6HRH4HRH3PTGES
	SCHEMBL235422	0.82	CYP2D6 (0.49)	CYP2D6HRH4HRH3TAAR1HTR6
	SCHEMBL3862497	0.81	LPL (0.37)	KIF11LPLLIPGPTGESPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.