Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16905604 | 0.86 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9APDGFRBKDR | |
| SCHEMBL22725265 | 0.86 | NPC1 (0.62) | SMN1; SMN2NPC1RAB9APDGFRBKDR | |
| SCHEMBL23343514 | 0.85 | KDM4E (0.40) | SMN1; SMN2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL23343419 | 0.81 | L3MBTL1 (0.37) | SMN1; SMN2NPC1RAB9APDGFRBKDR | |
| SCHEMBL30930844 | 0.75 | CHRNB2 (0.54) | SMN1; SMN2NPC1RAB9APDGFRBKDR | |
| SCHEMBL21074670 | 0.75 | CHRNB2 (0.54) | SMN1; SMN2NPC1RAB9APDGFRBKDR | |
| SCHEMBL18309474 | 0.74 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9APDGFRBKDR | |
| SCHEMBL23343395 | 0.72 | CHRNB2 (0.59) | ALDH1A1HPGDFGFR1MAPK1 | |
| SCHEMBL19561455 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9APDGFRBKDR | |
| SCHEMBL16905420 | 0.69 | KDM4E (0.46) | SMN1; SMN2NPC1RAB9AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11005050-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11005050-B2 | Metal complexes | SOD1, AP1M1, AP3M1 | SMN1; SMN2 3736/4885NPC1 3516/4885RAB9A 2201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.