Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 5/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.32 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.32 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.32 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.32 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.32 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.32 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.32 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.32 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.32 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.32 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.32 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.32 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.32 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.32 |
| ▸ | PSMA6 | P60900 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12846263 | 1.00 | GPR139 (0.34) | GPR139CA1CA2PSMB5PSMB1 | |
| SCHEMBL28921949 | 0.92 | CA1 (0.32) | GPR139CA1CA2PSMB5HDAC4 | |
| SCHEMBL12846265 | 0.92 | HDAC4 (0.38) | CA1CA2HDAC4CCR2 | |
| SCHEMBL12846262 | 0.90 | TTK (0.33) | CA1CA2HDAC4 | |
| Fluralaner SCHEMBL8515337 | 0.89 | CA1 (0.32) | CA1CA2HDAC4 | |
| Fluralaner SCHEMBL8513367 | 0.89 | CA1 (0.32) | CA1CA2HDAC4 | |
| Fluralaner SCHEMBL29399660 | 0.89 | CA1 (0.32) | CA1CA2HDAC4 | |
| Fluralaner SCHEMBL121934 | 0.89 | CA1 (0.32) | CA1CA2HDAC4 | |
| Fluralaner SCHEMBL29362559 | 0.89 | CA1 (0.32) | CA1CA2HDAC4 | |
| SCHEMBL737408 | 0.89 | EGLN1 (0.36) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473101-B1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS FOR FELINES | INTERVET INT BV (NL) | 2021-05-12 | — | — | EP | disclosed |