Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9906090 | 0.92 | MEN1 (0.46) | MEN1KMT2ARENFOLH1ALDH1A1 | |
| SCHEMBL12145378 | 0.90 | MEN1 (0.43) | MEN1KMT2ARENL3MBTL1GAA | |
| SCHEMBL23348162 | 0.89 | GAA (0.47) | MEN1KMT2ARENL3MBTL1GAA | |
| SCHEMBL19414268 | 0.87 | FOLH1 (0.41) | MEN1KMT2ARENFOLH1ALDH1A1 | |
| SCHEMBL21215983 | 0.86 | MEN1 (0.41) | MEN1KMT2ARENL3MBTL1GAA | |
| SCHEMBL24178479 | 0.85 | ALDH1A1 (0.47) | MEN1KMT2ARENALDH1A1NPSR1 | |
| SCHEMBL20018650 | 0.81 | REN (0.48) | MEN1KMT2ARENGAAALDH1A1 | |
| SCHEMBL9906098 | 0.79 | LMNA (0.53) | MEN1KMT2ARENGAAALDH1A1 | |
| SCHEMBL1373021 | 0.79 | MEN1 (0.53) | MEN1KMT2ARENL3MBTL1GAA | |
| SCHEMBL31657256 | 0.79 | CNR2 (0.54) | ZDHHC20LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11141357-B2 | Dental adhesive | DENTSPLY SIRONA INC. (US) | 2021-10-12 | — | — | US | disclosed |
| US-20210137795-A1 | DENTAL ADHESIVE | DENTSPLY SIRONA INC. (US) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11141357-B2 | Dental adhesive | CDH1, ITGA5, ICAM1 | MEN1 4054/4885KMT2A 2688/4885REN 4345/4885 |
| US-20210137795-A1 | DENTAL ADHESIVE | CDH1, ITGA5, ICAM1 | MEN1 4054/4885KMT2A 2688/4885REN 4345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.