Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | REN | P00797 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19414268 | 0.93 | FOLH1 (0.41) | MEN1KMT2ARENALDH1A1FOLH1 | |
| SCHEMBL24178479 | 0.93 | ALDH1A1 (0.47) | MEN1KMT2ARENALDH1A1LMNA | |
| SCHEMBL23348164 | 0.92 | MEN1 (0.39) | MEN1KMT2ARENALDH1A1FOLH1 | |
| SCHEMBL9906098 | 0.87 | LMNA (0.53) | MEN1KMT2ARENALDH1A1LMNA | |
| SCHEMBL31518844 | 0.86 | CNR2 (0.54) | RENLMNA | |
| SCHEMBL20275387 | 0.84 | CNR2 (0.56) | RENLMNA | |
| SCHEMBL25287086 | 0.84 | CNR2 (0.56) | RENLMNA | |
| SCHEMBL21734170 | 0.84 | CNR2 (0.56) | RENLMNA | |
| SCHEMBL9906101 | 0.84 | CNR2 (0.56) | RENLMNA | |
| SCHEMBL28301405 | 0.84 | HDAC6 (0.54) | RENLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DENTSPLY SIRONA INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20220031576-A1 | ADDITIVE MANUFACTURING PROCESS | DENTSPLY SIRONA INC. (US) | 2022-02-03 | — | — | US | disclosed |
| US-11224557-B2 | Dental composition | DENTSPLY SIRONA INC (US) | 2022-01-18 | — | — | US | disclosed |
| US-11166883-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2021-11-09 | — | — | US | disclosed |
| US-11116702-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2021-09-14 | — | — | US | disclosed |
| US-11110037-B2 | Methods and compositions to stabilize a nanogel and dental compositions therefrom | DENTSPLY SIRONA INC. (US) | 2021-09-07 | — | — | US | disclosed |
| US-20200405585-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2020-12-31 | — | — | US | disclosed |
| US-20200323743-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2020-10-15 | — | — | US | disclosed |
| WO-2020047217-A1 | METHODS AND COMPOSITIONS TO STABILIZE A NANOGEL AND DENTAL COMPOSITIONS THEREFROM | DENTSPLY SIRONA INC. (US) | 2020-03-05 | — | — | WO | disclosed |
| US-20200069530-A1 | METHODS AND COMPOSITIONS TO STABILIZE A NANOGEL AND DENTAL COMPOSITIONS THEREFROM | DENTSPLY SIRONA INC. (US) | 2020-03-05 | — | — | US | disclosed |
| US-20100160485-A1 | Hydrolysis stable self-etching, self-priming adhesive | KLEE JOACHIM | 2010-06-24 | — | — | US | disclosed |
| US-20100160485-A1 | Hydrolysis stable self-etching, self-priming adhesive | KLEE JOACHIM | 2010-06-24 | — | — | US | disclosed |
| US-20100022682-A1 | Dental adhesive composition | KLEE JOACHIM E | 2010-01-28 | — | — | US | disclosed |
| US-20100022682-A1 | Dental adhesive composition | KLEE JOACHIM E | 2010-01-28 | — | — | US | disclosed |
| US-20090043008-A1 | Dental adhesive | KLEE JOACHIM E | 2009-02-12 | — | — | US | disclosed |
| US-20090043008-A1 | Dental adhesive | KLEE JOACHIM E | 2009-02-12 | — | — | US | disclosed |
| US-20080194730-A1 | Hydrolysis stable self-etching, self-priming adhesive | KLEE JOACHIM | 2008-08-14 | — | — | US | disclosed |
| US-20080194730-A1 | Hydrolysis stable self-etching, self-priming adhesive | KLEE JOACHIM | 2008-08-14 | — | — | US | disclosed |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | DENTSPLY DE TREY GMBH (DE) | 2007-12-20 | — | — | US | disclosed |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | DENTSPLY DE TREY GMBH (DE) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11224557-B2 | Dental composition | GPX4, GPX1, NOXO1 | MEN1 4550/4885KMT2A 2671/4885REN 3671/4885 |
| US-20200069530-A1 | METHODS AND COMPOSITIONS TO STABILIZE A NANOGEL AND DENTAL COMPOSITIONS THEREFROM | TSG101, WASF2, RAB5IF | MEN1 4587/4885KMT2A 3819/4885REN 4815/4885 |
| US-20080194730-A1 | Hydrolysis stable self-etching, self-priming adhesive | PPA1, PHOSPHO1, PDAP1 | MEN1 3369/4885KMT2A 2589/4885REN 3546/4885 |
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DHX35, DHX30, FLNA | MEN1 3347/4885KMT2A 3471/4885REN 4313/4885 |
| US-20200323743-A1 | DENTAL COMPOSITION | F12, F11, F9 | MEN1 3657/4885KMT2A 2420/4885REN 4028/4885 |
| US-11110037-B2 | Methods and compositions to stabilize a nanogel and dental compositions therefrom | TSG101, WASF2, RAB5IF | MEN1 4587/4885KMT2A 3819/4885REN 4815/4885 |
| US-11116702-B2 | Dental composition | MTR, CAD, PAM | MEN1 4443/4885KMT2A 890/4885REN 4654/4885 |
| US-20100160485-A1 | Hydrolysis stable self-etching, self-priming adhesive | PPA1, PHOSPHO1, PDAP1 | MEN1 3369/4885KMT2A 2589/4885REN 3546/4885 |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | CAD, ASIC1, PDAP1 | MEN1 3704/4885KMT2A 2210/4885REN 4178/4885 |
| US-11166883-B2 | Dental composition | MSR1, TAS2R3, TAS2R39 | MEN1 1979/4885KMT2A 2600/4885REN 3493/4885 |
| US-20090043008-A1 | Dental adhesive | H1-0, H1-2, ITGA1 | MEN1 3501/4885KMT2A 949/4885REN 4023/4885 |
| US-20220031576-A1 | ADDITIVE MANUFACTURING PROCESS | FLNA, FLNB, SAMM50 | MEN1 150/4885KMT2A 4680/4885REN 4345/4885 |
| US-20200405585-A1 | DENTAL COMPOSITION | CBR3, CBR1, PRDX3 | MEN1 4873/4885KMT2A 4650/4885REN 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.