SCHEMBL23348409

SCHEMBL23348409

CC(C)(C)c1ccc2c(c1)c1ccc(C(C)(C)C)cc1n2-c1cc(-c2ccccc2)cc(-n2c3ccc(C(C)(C)C)cc3c3ccc(C(C)(C)C)cc32)c1C#N

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.34
DNMT1 P26358 3/20 0.32
RORC P51449 2/20 0.32
PGR P06401 1/20 0.32
RORA P35398 1/20 0.32
RORB Q92753 1/20 0.32
SERPINE1 P05121 1/20 0.31
NRP1 O14786 1/20 0.31
ALDH1A1 P00352 3/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
DHODH Q02127 1/20 0.31
KDM4E B2RXH2 2/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
HIF1A Q16665 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23348398 0.95 KIF11 (0.35) KIF11DNMT1SERPINE1NRP1ALDH1A1
SCHEMBL21840875 0.95 KIF11 (0.37) KIF11DNMT1RORCPGRRORA
SCHEMBL23348297 0.91 KIF11 (0.34) KIF11SERPINE1NRP1KDM4EMAPT
SCHEMBL23348464 0.90 SQOR (0.35) KIF11PGRSERPINE1KDM4ESMN1; SMN2
SCHEMBL23348416 0.89 PGR (0.35) KIF11PGRSERPINE1
SCHEMBL23348323 0.88 SMN1; SMN2 (0.39) KIF11SERPINE1NRP1ALDH1A1DHODH
SCHEMBL23348543 0.88 KCNH2 (0.36) KIF11PGRALDH1A1DHODHKDM4E
SCHEMBL28581529 0.88 ALDH1A1 (0.39) KIF11DNMT1ALDH1A1L3MBTL1KDM4E
SCHEMBL23348322 0.88 KIF11 (0.33) KIF11PGRSERPINE1NRP1ALDH1A1
SCHEMBL23348299 0.87 HTR1D (0.32) KIF11PGRDHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210139425-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210139425-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CCND2, CCND1, CRY1 KIF11 1724/4885DNMT1 2769/4885RORC 1165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.