Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 7/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | BRD1 | O95696 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717736 | 0.78 | L3MBTL1 (0.40) | POLBNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL23348985 | 0.72 | CA12 (0.39) | POLBCA12CA1CA2CA9 | |
| SCHEMBL3179087 | 0.71 | TSHR (0.53) | POLBNPC1RAB9AALDH1A1CYP2C19 | |
| SCHEMBL3194309 | 0.71 | L3MBTL1 (0.50) | POLBALDH1A1CYP2C19KDM4EKMT2A | |
| SCHEMBL7991950 | 0.69 | ALDH1A1 (0.33) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL28417940 | 0.65 | — | — | |
| SCHEMBL31749473 | 0.65 | PIK3CD (0.48) | NPC1RAB9AALDH1A1CYP1A2LMNA | |
| SCHEMBL19640293 | 0.65 | CLK1 (0.34) | — | |
| SCHEMBL10299240 | 0.64 | POLB (0.54) | POLBALDH1A1HPGDCA12CA1 | |
| SCHEMBL18121475 | 0.64 | POLB (0.84) | POLBAPAF1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210138385-A1 | METAL-ORGANIC FRAMEWORKS CONTAINING METAL-HYDROXIDE MOIETIES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2021-05-13 | — | — | US | disclosed |