Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717736 | 0.74 | L3MBTL1 (0.40) | CA12CA9CA1CA2POLB | |
| SCHEMBL23348987 | 0.72 | POLB (0.44) | CA12CA9CA1CA2POLB | |
| SCHEMBL5916658 | 0.72 | METAP2 (0.52) | POLBTP53KDM4E | |
| SCHEMBL6675514 | 0.70 | CA12 (0.65) | CA12CA9CA1CA2POLB | |
| SCHEMBL7991950 | 0.68 | ALDH1A1 (0.33) | KDM4EGAA | |
| SCHEMBL242787 | 0.67 | ALDH1A1 (0.48) | POLBKDM4EGAAMAPK1ESR1 | |
| SCHEMBL3179087 | 0.67 | TSHR (0.53) | POLBKDM4E | |
| SCHEMBL3194336 | 0.67 | L3MBTL1 (0.50) | POLBKDM4E | |
| SCHEMBL31749473 | 0.67 | PIK3CD (0.48) | TP53KDM4EMAPK1 | |
| SCHEMBL19640293 | 0.67 | CLK1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210138385-A1 | METAL-ORGANIC FRAMEWORKS CONTAINING METAL-HYDROXIDE MOIETIES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2021-05-13 | — | — | US | disclosed |