Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.85 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.85 |
| ▸ | HTR1A | P08908 | 3/20 | 0.85 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.85 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.85 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.85 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.85 |
| ▸ | DRD1 | P21728 | 3/20 | 0.85 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.85 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.85 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.85 |
| ▸ | DRD3 | P35462 | 3/20 | 0.85 |
| ▸ | THPO | P40225 | 3/20 | 0.85 |
| ▸ | MTOR | P42345 | 3/20 | 0.85 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.85 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.85 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.85 |
| ▸ | NPC1 | O15118 | 2/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoperazine SCHEMBL28057424 | 0.97 | FPR2 (0.86) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| SCHEMBL10168901 | 0.96 | FPR2 (0.80) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| SCHEMBL30612615 | 0.96 | FPR2 (0.80) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| Triflupromazine SCHEMBL32668886 | 0.92 | CYP1A2 (1.00) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| Triflupromazine SCHEMBL44085 | 0.92 | CYP1A2 (1.00) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| Triflupromazine SCHEMBL30903901 | 0.91 | LMNA (1.00) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| Triflupromazine SCHEMBL29419087 | 0.91 | LMNA (1.00) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| Triflupromazine SCHEMBL317144 | 0.91 | LMNA (1.00) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| SCHEMBL4283601 | 0.90 | TP53 (0.76) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| Triflupromazine SCHEMBL317145 | 0.90 | CYP1A2 (0.95) | TP53MAPK1CYP1A2ABCB1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210137938-A1 | NUPR1 INHIBITION FOR TREATING CANCER | UNIVERSITÉ D'AIX-MARSEILLE (FR) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210137938-A1 | NUPR1 INHIBITION FOR TREATING CANCER | NUP188, NUP160, NUP50 | TP53 129/4885MAPK1 2549/4885CYP1A2 4499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.