Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.36 |
| ▸ | CHRNG | P07510 | 2/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23355178 | 0.82 | ITGB2 (0.48) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL23355170 | 0.76 | TYK2 (0.45) | ALDH1A1SMN1; SMN2SLC6A2CHRNA1CHRNG | |
| SCHEMBL30695663 | 0.75 | GAA (0.54) | RAB9AALDH1A1MEN1KMT2AHTT | |
| SCHEMBL23355193 | 0.74 | ITGA4 (0.48) | SMN1; SMN2LMNAMAPK1ITGB1ITGA4 | |
| SCHEMBL5700509 | 0.74 | SMN1; SMN2 (0.54) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23355180 | 0.73 | CAPN1 (0.49) | L3MBTL1ITGB1ITGA4 | |
| SCHEMBL29961792 | 0.72 | CAPN1 (0.58) | L3MBTL1ITGB1ITGA4ITGB2ICAM1 | |
| SCHEMBL24008799 | 0.72 | CAPN1 (0.58) | L3MBTL1ITGB1ITGA4ITGB2ICAM1 | |
| SCHEMBL1287117 | 0.72 | PGR (0.47) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3495542 | 0.72 | PGR (0.47) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820864-A1 | METHODS OF TREATING LIVER FIBROSIS USING CALPAIN INHIBITORS | Blade Therapeutics, Inc. (US) | 2021-05-19 | — | — | EP | disclosed |