Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709682 | 0.92 | FTO (0.39) | SLC6A3SLC6A4ALDH1A1HPGDACR | |
| SCHEMBL2336114 | 0.91 | LTB4R2 (0.37) | ALDH1A1HPGDACRFTOLTB4R2 | |
| SCHEMBL3711509 | 0.84 | ACR (0.36) | ALDH1A1HPGDACRFTOKDM4E | |
| SCHEMBL2332523 | 0.84 | MAPT (0.40) | ALDH1A1HPGDACRFTOKDM4E | |
| SCHEMBL2342592 | 0.84 | LPAR1 (0.39) | SLC6A3SLC6A4ALDH1A1HPGDSLC6A2 | |
| SCHEMBL3711309 | 0.83 | FTO (0.36) | ALDH1A1HPGDACRFTOLTB4R2 | |
| SCHEMBL2336634 | 0.83 | LPAR1 (0.43) | ALDH1A1HPGDACRFTOKDM4E | |
| SCHEMBL2335317 | 0.82 | LPAR1 (0.38) | ALDH1A1HPGDKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL3714395 | 0.81 | NR1H4 (0.40) | ALDH1A1HPGDACRFTOSMN1; SMN2 | |
| SCHEMBL3704916 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HPGDACRFTOKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358688-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | Amira Pharmaceuticals, Inc. (US) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2010077883-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |