Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | ACR | P10323 | 1/20 | 0.34 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2339543 | 0.94 | LPAR1 (0.42) | LPAR1LPAR2LPAR3ALDH1A1L3MBTL1 | |
| SCHEMBL3708634 | 0.93 | ALDH1A1 (0.42) | LPAR1LPAR2LPAR3ALDH1A1L3MBTL1 | |
| SCHEMBL3707582 | 0.91 | LPAR1 (0.39) | LPAR1LPAR2LPAR3ALDH1A1L3MBTL1 | |
| SCHEMBL3700510 | 0.91 | LPAR1 (0.36) | LPAR1LPAR2LPAR3ALDH1A1L3MBTL1 | |
| SCHEMBL2338262 | 0.91 | LPAR1 (0.50) | LPAR1LPAR2LPAR3HTT | |
| SCHEMBL3714445 | 0.89 | LPAR1 (0.38) | LPAR1LPAR2LPAR3ALDH1A1L3MBTL1 | |
| SCHEMBL3709586 | 0.89 | LPAR1 (0.38) | LPAR1LPAR2LPAR3ALDH1A1L3MBTL1 | |
| SCHEMBL3713548 | 0.88 | LPAR1 (0.37) | LPAR1LPAR2LPAR3ALDH1A1L3MBTL1 | |
| SCHEMBL3717698 | 0.88 | P2RX3 (0.38) | LPAR1LPAR2LPAR3ALDH1A1L3MBTL1 | |
| SCHEMBL3704161 | 0.87 | LPAR1 (0.47) | LPAR1LPAR2LPAR3ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | claimed |
| EP-2358688-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | Amira Pharmaceuticals, Inc. (US) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010077883-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |