Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.51 |
| ▸ | CFTR | P13569 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28259523 | 0.98 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CFTRTSHRHPGD | |
| SCHEMBL33469 | 0.88 | HCAR2 (0.50) | ALDH1A1HSD17B10TSHRHPGDSMN1; SMN2 | |
| SCHEMBL2849416 | 0.84 | MAPT (0.64) | ALDH1A1HSD17B10CFTRTSHRHPGD | |
| SCHEMBL2849418 | 0.84 | MAPT (0.64) | ALDH1A1HSD17B10CFTRTSHRHPGD | |
| SCHEMBL28839863 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HSD17B10CFTRTSHRHPGD | |
| SCHEMBL7299840 | 0.81 | HPGD (0.51) | ALDH1A1HSD17B10TSHRHPGDSMN1; SMN2 | |
| SCHEMBL2367627 | 0.80 | ALDH1A1 (0.69) | ALDH1A1HSD17B10CFTRTSHRHPGD | |
| SCHEMBL21694738 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CFTRTSHRHPGD | |
| SCHEMBL240024 | 0.79 | HSD17B10 (0.65) | ALDH1A1HSD17B10TSHRHPGDSMN1; SMN2 | |
| SCHEMBL28056289 | 0.78 | ALDH1A1 (0.62) | ALDH1A1HSD17B10CFTRTSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240050598-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TETROFOSMIN AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | JUBILANT DRAXIMAGE INC. (CA) | 2024-02-15 | — | — | US | disclosed |
| US-20210145987-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TETROFOSMIN AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | Jubilant Generics Limited (IN) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210145987-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TETROFOSMIN AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | TREH, TYMP, PRCP | ALDH1A1 4783/4885HSD17B10 4728/4885CFTR 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.