Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 7/20 | 0.39 |
| ▸ | JAK2 | O60674 | 5/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23360531 | 1.00 | KEAP1 (0.42) | KEAP1NOS2RPS6KB1MEN1ALDH1A1 | |
| SCHEMBL23360399 | 1.00 | KEAP1 (0.42) | KEAP1NOS2RPS6KB1MEN1ALDH1A1 | |
| SCHEMBL23360592 | 0.91 | HTR1A (0.46) | NOS2RPS6KB1MEN1ALDH1A1KMT2A | |
| SCHEMBL23360595 | 0.91 | HTR1A (0.46) | NOS2RPS6KB1MEN1ALDH1A1KMT2A | |
| SCHEMBL23360439 | 0.87 | TP53 (0.43) | KEAP1NOS2RPS6KB1MEN1ALDH1A1 | |
| SCHEMBL23360161 | 0.87 | KDM4E (0.40) | RPS6KB1L3MBTL1JAK3JAK2KDM5A | |
| SCHEMBL23360158 | 0.87 | KDM4E (0.40) | RPS6KB1L3MBTL1JAK3JAK2KDM5A | |
| SCHEMBL23360172 | 0.87 | KDM4E (0.40) | RPS6KB1L3MBTL1JAK3JAK2KDM5A | |
| SCHEMBL23359904 | 0.86 | PDE4D (0.45) | NOS2RPS6KB1ALDH1A1JAK3JAK2 | |
| SCHEMBL23360381 | 0.86 | PDE4D (0.45) | NOS2RPS6KB1ALDH1A1JAK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655235-B2 | Pyrrolidine and piperidine compounds | YUHAN CORPORATION (KR) | 2023-05-23 | — | — | US | disclosed |
| EP-4055014-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | Yuhan Corporation (KR) | 2022-09-14 | — | — | EP | disclosed |
| US-20210147386-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | YUHAN CORPORATION (KR) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655235-B2 | Pyrrolidine and piperidine compounds | FAP, APC, VHL | KEAP1 3110/4885NOS2 1575/4885RPS6KB1 2542/4885 |
| US-20210147386-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | FAP, APC, VHL | KEAP1 3110/4885NOS2 1575/4885RPS6KB1 2542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.