Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 3/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.38 |
| ▸ | BTK | Q06187 | 3/20 | 0.38 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23360595 | 1.00 | HTR1A (0.46) | HTR1AADRA1DADRA1AADRA1BJAK3 | |
| SCHEMBL23360399 | 0.91 | KEAP1 (0.42) | JAK3NOS2RPS6KB1MEN1ALDH1A1 | |
| SCHEMBL23360531 | 0.91 | KEAP1 (0.42) | JAK3NOS2RPS6KB1MEN1ALDH1A1 | |
| SCHEMBL23360402 | 0.91 | KEAP1 (0.42) | JAK3NOS2RPS6KB1MEN1ALDH1A1 | |
| SCHEMBL23360516 | 0.87 | CDK2 (0.43) | JAK3BTKMAPK1PIM1PIM2 | |
| SCHEMBL23360023 | 0.87 | JAK3 (0.42) | JAK3PAK1MEN1ALDH1A1KMT2A | |
| SCHEMBL23360514 | 0.87 | CDK2 (0.43) | JAK3BTKMAPK1PIM1PIM2 | |
| SCHEMBL23360026 | 0.87 | JAK3 (0.42) | JAK3PAK1MEN1ALDH1A1KMT2A | |
| SCHEMBL23360169 | 0.86 | HTR1A (0.49) | HTR1AADRA1DADRA1AADRA1BNOS2 | |
| SCHEMBL23360171 | 0.86 | HTR1A (0.49) | HTR1AADRA1DADRA1AADRA1BNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655235-B2 | Pyrrolidine and piperidine compounds | YUHAN CORPORATION (KR) | 2023-05-23 | — | — | US | disclosed |
| EP-4055014-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | Yuhan Corporation (KR) | 2022-09-14 | — | — | EP | disclosed |
| US-20210147386-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | YUHAN CORPORATION (KR) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655235-B2 | Pyrrolidine and piperidine compounds | FAP, APC, VHL | HTR1A 4160/4885ADRA1D 3563/4885ADRA1A 4172/4885 |
| US-20210147386-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | FAP, APC, VHL | HTR1A 4160/4885ADRA1D 3563/4885ADRA1A 4172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.