Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23360640 | 0.83 | HTR2A (0.55) | NR4A2HTR2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL3279608 | 0.81 | BRPF1 (0.55) | NR4A2HTR2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL19100705 | 0.81 | CTSL (0.58) | MAPTSMN1; SMN2POLBCTSLCTSS | |
| SCHEMBL22882661 | 0.78 | TACR1 (0.57) | NR4A2MAPTSMN1; SMN2SOS2CTSL | |
| SCHEMBL13656743 | 0.78 | NQO2 (0.51) | L3MBTL1HDAC10HDAC6KCNA5RAB9A | |
| SCHEMBL27067022 | 0.78 | MTNR1A (0.55) | HTR2AMAPTL3MBTL1PARP1MTNR1A | |
| SCHEMBL14887049 | 0.77 | PIM1 (0.55) | MAPTL3MBTL1HDAC10HDAC6KCNA5 | |
| SCHEMBL30344301 | 0.77 | KCNA5 (0.47) | L3MBTL1HDAC10HDAC6KCNA5POLB | |
| SCHEMBL23127300 | 0.77 | ATM (0.53) | MAPTSMN1; SMN2SOS2HDAC10HDAC6 | |
| SCHEMBL29378363 | 0.77 | ATM (0.53) | MAPTSMN1; SMN2SOS2HDAC10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210147405-A1 | BICYCLIC HETEROAROMATIC UREA OR CARBAMATE COMPOUNDS FOR USE IN THERAPY | EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) | 2021-05-20 | — | — | US | disclosed |
| CN-111032654-A | Bicyclic heteroaromatic urea or carbamate compounds for use in therapy | 欧洲分子生物学实验室 | 2020-04-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147405-A1 | BICYCLIC HETEROAROMATIC UREA OR CARBAMATE COMPOUNDS FOR USE IN THERAPY | HIF1A, HIF1AN, EGLN3 | NR4A2 920/4885HTR2A 3750/4885MAPT 1519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.