Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | AXL | P30530 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30058841 | 1.00 | ADRB2 (0.68) | ADRB2MAPK1MAPTDRD2DRD3 | |
| SCHEMBL5310874 | 0.85 | MAPK1 (0.69) | ADRB2MAPK1MAPTDRD2DRD3 | |
| SCHEMBL6125222 | 0.84 | ADRB2 (0.72) | ADRB2MAPK1MAPTDRD2DRD3 | |
| SCHEMBL6595059 | 0.82 | ADRB2 (0.73) | ADRB2MAPK1MAPTDRD2DRD3 | |
| SCHEMBL2711296 | 0.81 | ADRB2 (1.00) | ADRB2MAPK1MAPTDRD2DRD3 | |
| SCHEMBL30058924 | 0.81 | ADRB2 (1.00) | ADRB2MAPK1MAPTDRD2DRD3 | |
| SCHEMBL3863739 | 0.81 | NCF1 (0.70) | ADRB2MAPK1MAPTDRD2DRD3 | |
| SCHEMBL23362808 | 0.81 | MAPK1 (0.82) | ADRB2MAPK1MAPTDRD2DRD3 | |
| SCHEMBL23373387 | 0.80 | NCF1 (0.69) | ADRB2MAPK1MAPTMEN1KMT2A | |
| SCHEMBL895026 | 0.79 | ADRB2 (0.64) | ADRB2MAPK1MAPTDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402890-A1 | NOVEL QUINOLINE COMPOUND AND USE THEREOF | MBD CO., LTD (KR) | 2022-12-22 | — | — | US | claimed |
| WO-2022235091-A1 | NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF | 엠비디 주식회사 | 2022-11-10 | — | — | WO | claimed |
| US-20220402890-A1 | NOVEL QUINOLINE COMPOUND AND USE THEREOF | MBD CO., LTD (KR) | 2022-12-22 | — | — | US | disclosed |
| WO-2022235091-A1 | NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF | 엠비디 주식회사 | 2022-11-10 | — | — | WO | disclosed |
| WO-2021096335-A1 | NOVEL QUINOLINE COMPOUND AND USE THEREOF | 엠비디 주식회사 | 2021-05-20 | — | — | WO | disclosed |
| WO-2021096335-A1 | NOVEL QUINOLINE COMPOUND AND USE THEREOF | 엠비디 주식회사 | 2021-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402890-A1 | NOVEL QUINOLINE COMPOUND AND USE THEREOF | CYP4A11, CYP4B1, CYP4A22 | ADRB2 1242/4885MAPK1 1610/4885MAPT 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.