Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23364540 | 1.00 | GPR119 (0.36) | GPR119L3MBTL1STAT3HTR7ALDH1A1 | |
| SCHEMBL23364354 | 0.81 | HTR7 (0.52) | HTR7 | |
| SCHEMBL23364538 | 0.81 | HTR7 (0.52) | HTR7 | |
| SCHEMBL21552587 | 0.80 | GPR119 (0.36) | GPR119L3MBTL1STAT3ALDH1A1HPGD | |
| SCHEMBL21552627 | 0.80 | GPR119 (0.36) | GPR119L3MBTL1STAT3ALDH1A1HPGD | |
| SCHEMBL12495895 | 0.78 | PDK1 (0.42) | L3MBTL1STAT3ALDH1A1 | |
| SCHEMBL2389377 | 0.76 | ALDH1A1 (0.45) | GPR119STAT3ALDH1A1 | |
| SCHEMBL23364149 | 0.75 | CYP2D6 (0.37) | L3MBTL1STAT3HTR7ALDH1A1HPGD | |
| SCHEMBL21552625 | 0.75 | ALDH1A1 (0.34) | L3MBTL1STAT3HTR7ALDH1A1HPGD | |
| SCHEMBL23364148 | 0.75 | CYP2D6 (0.37) | L3MBTL1STAT3HTR7ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021097117-A2 | NOVEL FUNCTIONALIZED LACTONES AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-05-20 | — | — | WO | disclosed |