Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 5/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.36 |
| ▸ | PBK | Q96KB5 | 8/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201225 | 0.78 | PDE4A (0.41) | ADORA1CDK9DYRK1A | |
| SCHEMBL30622669 | 0.77 | RAB9A (0.35) | PDGFRBPDGFRA | |
| SCHEMBL2335278 | 0.75 | PBK (0.48) | PBKADORA1SLC6A3 | |
| SCHEMBL2332188 | 0.74 | PBK (0.52) | PBKSLC6A3 | |
| SCHEMBL30622632 | 0.68 | HSD17B10 (0.39) | — | |
| SCHEMBL4611131 | 0.67 | ALDH1A1 (0.46) | CDK9DYRK1A | |
| SCHEMBL4420447 | 0.67 | NQO2 (0.46) | CDK9DYRK1A | |
| SCHEMBL24834182 | 0.66 | DCPS (0.47) | CDK9DYRK1A | |
| SCHEMBL941422 | 0.66 | KEAP1 (0.47) | CDK9DYRK1A | |
| SCHEMBL2549634 | 0.66 | NQO2 (0.44) | CDK9DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358365-A1 | GLYCOGEN SYNTHASE KINASE-3 BETA INHIBITORS CONTAINING 7-HYDROXY-BENZOIMIDAZOLE-4-YL-METHANONE DERIVATIVES | Oncotherapy Science, Inc. (JP) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010058512-A1 | GLYCOGEN SYNTHASE KINASE-3 BETA INHIBITORS CONTAINING 7-HYDROXY-BENZOIMIDAZOLE-4-YL-METHANONE DERIVATIVES | ONCOTHERAPY SCIENCE, INC. (JP) | 2010-05-27 | — | — | WO | disclosed |