Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 7/20 | 0.46 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16789829 | 0.81 | NPC1 (0.39) | NQO2DCPSALDH1A1HPGDNPC1 | |
| SCHEMBL4611131 | 0.81 | ALDH1A1 (0.46) | NQO2DCPSKEAP1NFE2L2CDK9 | |
| SCHEMBL24834182 | 0.80 | DCPS (0.47) | NQO2DCPSKEAP1NFE2L2CDK9 | |
| SCHEMBL6935072 | 0.80 | NQO2 (0.44) | NQO2DCPSKEAP1NFE2L2CDK9 | |
| SCHEMBL28127254 | 0.80 | CDK9 (0.46) | NQO2DCPSKEAP1NFE2L2CDK9 | |
| SCHEMBL2549634 | 0.80 | NQO2 (0.44) | NQO2DCPSKEAP1NFE2L2CDK9 | |
| SCHEMBL31723877 | 0.80 | DCPS (0.47) | NQO2DCPSKEAP1NFE2L2CDK9 | |
| SCHEMBL941422 | 0.80 | KEAP1 (0.47) | NQO2DCPSKEAP1NFE2L2CDK9 | |
| SCHEMBL6650617 | 0.80 | CDK9 (0.46) | NQO2DCPSKEAP1NFE2L2CDK9 | |
| SCHEMBL1041136 | 0.78 | PLAUR (0.50) | NQO2DCPSCDK9DYRK1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| US-20250161269-A1 | COMPOSITIONS AND METHODS FOR PERIPHERAL TARGETING OF MELATONIN RECEPTOR AGONIST | CELMATIX INC. | 2025-05-22 | — | — | US | disclosed |
| EP-2766359-A2 | HETEROCYCLIC COMPOUNDS AND USE THEREOF AS MODULATORS OF TYPE III RECEPTOR TYROSINE KINASES | Ambit Biosciences Corporation (US) | 2014-08-20 | — | — | EP | disclosed |
| WO-2013056070-A2 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2013-04-18 | — | — | WO | disclosed |
| US-7527953-B2 | Genes from Propionibacterium freudenreichii encoding enzymes involved in vitamin B12 biosynthesis | DSM IP ASSETS B.V. (NL) | 2009-05-05 | — | — | US | disclosed |
| US-20060183188-A1 | Genes from propionibacterium freudenreichii encoding enzymes involved in vitamin b12 biosynthesis | DSM IP ASSETS B.V. (NL) | 2006-08-17 | — | — | US | disclosed |
| EP-1525303-A1 | GENES FROM PROPIONIBACTERIUM FREUDENREICHII ENCODING ENZYMES INVOLVED IN VITAMIN B12 BIOSYNTHESIS | DSM IP Assets B.V. (NL) | 2005-04-27 | — | — | EP | disclosed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |
| WO-2004011635-A1 | GENES FROM PROPIONIBACTERIUM FREUDENREICHII ENCODING ENZYMES INVOLVED IN VITAMIN B12 BIOSYNTHESIS | DSM IP ASSETS B.V. (NL) | 2004-02-05 | — | — | WO | disclosed |
| EP-0865281-B1 | NAPHTHYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTICOAGULANTS | BERLEX LAB (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-0865281-A4 | NAPHTHYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTICOAGULANTS | BERLEX LAB (US) | 1999-07-28 | — | — | EP | disclosed |
| US-5849759-A | Naphthyl-substituted benzimidazole derivatives as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0865281-A1 | NAPHTHYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTICOAGULANTS | BERLEX LABORATORIES, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997021437-A1 | NAPHTHYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTICOAGULANTS | BERLEX LABORATORIES, INC. (DE) | 1997-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183188-A1 | Genes from propionibacterium freudenreichii encoding enzymes involved in vitamin b12 biosynthesis | COASY, AMD1, BLVRB | NQO2 250/4885DCPS 178/4885KEAP1 3005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.