SCHEMBL23366165

SCHEMBL23366165

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nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MME P08473 5/20 0.40
CA2 P00918 3/20 0.38
CA4 P22748 1/20 0.38
FNTA P49354 2/20 0.33
FNTB P49356 2/20 0.33
PKLR P30613 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
LMNA P02545 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CA1 P00915 1/20 0.32
CASP3 P42574 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25206156 0.78 LMNA (0.47) MMECA2CA4PKLRGAA
SCHEMBL25206154 0.78 LMNA (0.47) MMECA2CA4PKLRGAA
SCHEMBL23366213 0.76 ENPEP (0.30)
SCHEMBL7898517 0.73 MME (0.46) MMECA2CA4PKLRGAA
SCHEMBL23967395 0.73 MME (0.46) MMECA2CA4PKLRGAA
SCHEMBL28910144 0.72 MME (0.45) MMECA2CA4PKLRGAA
SCHEMBL30826516 0.71 ITGB3 (0.44) MMECA2CA4MAPTLMNA
SCHEMBL23366205 0.69
SCHEMBL23366220 0.69
SCHEMBL21841573 0.69 PKLR (0.37) MMECA2CA4PKLRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3377487-B1 COMPOUNDS FOR MEDICINAL APPLICATIONS AusVir Therapeutics Pty Ltd (AU) 2022-01-12 EP disclosed
US-11007274-B2 Compounds for medicinal applications AusVir Therapeutics Pty Ltd (AU) 2021-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11007274-B2 Compounds for medicinal applications HAVCR2, ENGASE, DNPEP MME 14/4885CA2 246/4885CA4 289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.