Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | ECE1 | P42892 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CASP9 | P55211 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 3/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23366189 | 0.90 | PSMB5 (0.36) | PSMB5RENMMEECE1LMNA | |
| SCHEMBL23366221 | 0.90 | PSMB5 (0.36) | PSMB5RENMMEECE1LMNA | |
| SCHEMBL24180261 | 0.88 | PSMB5 (0.34) | PSMB5RENMMEECE1LMNA | |
| SCHEMBL23366217 | 0.75 | MMP13 (0.40) | PSMB5RENMMEECE1CASP1 | |
| SCHEMBL23366239 | 0.74 | CTSS (0.35) | PSMB5ALDH1A1CYP1A2MMP9CTSL | |
| SCHEMBL23366160 | 0.74 | CASP3 (0.41) | MMEECE1CASP1CASP3CASP7 | |
| SCHEMBL23366166 | 0.72 | CASP1 (0.47) | MMEECE1LMNACASP1CASP3 | |
| SCHEMBL23366204 | 0.72 | ALDH1A1 (0.34) | PSMB5ALDH1A1CYP1A2MMP9CTSL | |
| SCHEMBL23366191 | 0.69 | MMP13 (0.39) | MMEECE1CASP3CTSK | |
| SCHEMBL23366235 | 0.69 | MMP13 (0.39) | MMEECE1CASP3CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11007274-B2 | Compounds for medicinal applications | AusVir Therapeutics Pty Ltd (AU) | 2021-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11007274-B2 | Compounds for medicinal applications | HAVCR2, ENGASE, DNPEP | PSMB5 4581/4885REN 1340/4885MME 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.