Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 14/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | FCER2 | P06734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23366233 | 0.88 | MME (0.48) | CASP1CTSLHTT | |
| SCHEMBL24180285 | 0.81 | MME (0.39) | CASP1CTSL | |
| SCHEMBL23366160 | 0.81 | CASP3 (0.41) | CASP1 | |
| SCHEMBL23366227 | 0.80 | ALDH1A1 (0.44) | HTT | |
| SCHEMBL11280295 | 0.78 | CASP1 (0.47) | CASP1 | |
| SCHEMBL8553630 | 0.78 | CASP1 (0.64) | CASP1CTSL | |
| SCHEMBL6159279 | 0.78 | CASP1 (0.64) | CASP1CTSL | |
| SCHEMBL23366217 | 0.78 | MMP13 (0.40) | CASP1CTSL | |
| SCHEMBL29443514 | 0.72 | CASP1 (0.48) | CASP1HTT | |
| SCHEMBL23937684 | 0.72 | SLC15A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11007274-B2 | Compounds for medicinal applications | AusVir Therapeutics Pty Ltd (AU) | 2021-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11007274-B2 | Compounds for medicinal applications | HAVCR2, ENGASE, DNPEP | CASP1 2204/4885CTSL 418/4885PTPN1 2458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.