Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CAD | P27708 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23367181 | 0.79 | PIK3CD (0.32) | — | |
| SCHEMBL17034712 | 0.67 | CYP1A2 (0.41) | PKMHTTALDH1A1HPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL18334522 | 0.65 | MMP8 (0.40) | PKMKDM4EHTTALDH1A1HPGD | |
| SCHEMBL23367183 | 0.64 | MAOA (0.38) | ALDH1A1MEN1KMT2A | |
| SCHEMBL13070248 | 0.64 | ALDH1A1 (0.42) | HTTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL20569154 | 0.64 | ALDH1A1 (0.42) | PKMHTTALDH1A1HPGDMEN1 | |
| SCHEMBL23366825 | 0.63 | TDP1 (0.33) | KDM4E | |
| SCHEMBL13537856 | 0.61 | ALDH1A1 (0.43) | ALDH1A1HPGDMEN1KMT2AALOX15 | |
| SCHEMBL803891 | 0.61 | ALDH1A1 (0.43) | ALDH1A1HPGDMEN1KMT2AALOX15 | |
| SCHEMBL803804 | 0.61 | ALDH1A1 (0.43) | ALDH1A1HPGDMEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822265-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer AG (DE) | 2021-05-19 | — | — | EP | disclosed |