Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20984340 | 0.81 | EPHX2 (0.59) | TGM2EPHX2TRPV1KIF11NPC1 | |
| SCHEMBL1978109 | 0.79 | EPHX2 (0.57) | TGM2EPHX2TRPV1KIF11NPC1 | |
| SCHEMBL28980360 | 0.78 | CYP3A4 (0.57) | TGM2EPHX2TRPV1KIF11NPC1 | |
| SCHEMBL9302776 | 0.78 | KIF11 (0.61) | TGM2EPHX2TRPV1KIF11NPC1 | |
| SCHEMBL16312776 | 0.76 | ALDH5A1 (0.46) | RAB9AALDH1A1 | |
| SCHEMBL26887415 | 0.76 | GAA (0.55) | TGM2TRPV1NPC1RAB9AMAOB | |
| SCHEMBL16312775 | 0.75 | ALOX5 (0.57) | TGM2ALDH1A1LMNA | |
| SCHEMBL15540929 | 0.75 | EPHX2 (0.47) | TGM2EPHX2TRPV1KIF11NPC1 | |
| SCHEMBL28191918 | 0.74 | GAA (0.62) | TGM2EPHX2TRPV1KIF11NPC1 | |
| SCHEMBL28871731 | 0.72 | ALDH1A1 (0.58) | EPHX2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822265-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer AG (DE) | 2021-05-19 | — | — | EP | disclosed |