Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20984340 | 0.84 | EPHX2 (0.59) | KIF11EPHX2PTGS1TGM2NPC1 | |
| SCHEMBL5075214 | 0.83 | PEPD (0.52) | KIF11NPC1CA1CA2ALDH1A1 | |
| SCHEMBL1978109 | 0.82 | EPHX2 (0.57) | KIF11EPHX2PTGS1TGM2NPC1 | |
| SCHEMBL28980360 | 0.81 | CYP3A4 (0.57) | KIF11EPHX2TGM2NPC1RAB9A | |
| SCHEMBL167549 | 0.80 | KIF11 (0.89) | KIF11EPHX2PTGS1TGM2NPC1 | |
| SCHEMBL11798167 | 0.79 | KIF11 (0.61) | KIF11PTGS1RAB9ACA1CA2 | |
| SCHEMBL23367251 | 0.78 | TGM2 (0.53) | KIF11EPHX2PTGS1TGM2NPC1 | |
| SCHEMBL6156958 | 0.78 | ALDH1A1 (0.63) | TGM2CA1CA2ALDH1A1GAA | |
| SCHEMBL9179118 | 0.77 | PEPD (0.64) | NPC1CA1CA2ALDH1A1GAA | |
| SCHEMBL8665919 | 0.77 | EPHX2 (0.59) | KIF11EPHX2NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328915-A | Insecticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-12 | — | — | US | disclosed |